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Regenerating Activity of Citrus Aurantifolia on Paracetamol Induced Heaptic Damage


Affiliations
1 Department of Biochemistry, Marudu Pandiyar College, Thanjavur (T.N.), India
2 Department of Environmental and Herbal Sciences, Tamil University, Thanjavur (T.N.), India
     

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Liver regulates many important metabolic functions. Hepatic injury is associated with distoration of these metabolic functions. Thus liver disease remains one of the serious health problems. Inspite of tremendous studies in modern medicine, there are not much drugs available for the treatment of liver disorders. In the present study, paracetamol was used to induce the hepatic damage. Paracetamol, is a widely used analgesic and antipyretic drug. Oxidative stress is reported to play an important role in the pathogenesis of paracetamol – induced liver damage. The result confirm that Citrus aurantifolia possess a potential hepatoprotective activity.

Keywords

Liver, Paracetamol, Citrus aurantifolia and Phytochemicals.
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  • Regenerating Activity of Citrus Aurantifolia on Paracetamol Induced Heaptic Damage

Abstract Views: 271  |  PDF Views: 0

Authors

K. Gokulakrishnan
Department of Biochemistry, Marudu Pandiyar College, Thanjavur (T.N.), India
P. Senthamilselvan
Department of Biochemistry, Marudu Pandiyar College, Thanjavur (T.N.), India
V. Sivakumari
Department of Environmental and Herbal Sciences, Tamil University, Thanjavur (T.N.), India

Abstract


Liver regulates many important metabolic functions. Hepatic injury is associated with distoration of these metabolic functions. Thus liver disease remains one of the serious health problems. Inspite of tremendous studies in modern medicine, there are not much drugs available for the treatment of liver disorders. In the present study, paracetamol was used to induce the hepatic damage. Paracetamol, is a widely used analgesic and antipyretic drug. Oxidative stress is reported to play an important role in the pathogenesis of paracetamol – induced liver damage. The result confirm that Citrus aurantifolia possess a potential hepatoprotective activity.

Keywords


Liver, Paracetamol, Citrus aurantifolia and Phytochemicals.