Asian Journal of Bio Science

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Genetic Markers of Antibiotic Resistance


Affiliations
1 Division of Bacteriology and Mycology, Indian Veterinary Research Institute, Izatnagar, Bareilly (U.P.), India
2 Division of Virology, Indian Veterinary Research Institute, Izatnagar, Bareilly (U.P.), India
     

   Subscribe/Renew Journal


The failure of antibiotic therapy in human and veterinary medicine has called the world community into a threatening situation. Various measures have been by policy makers across the globe to combat the issue of antimicrobial resistance. The massive problem of therapeutic failure has microelements as its source. This minireview discusses about the genetic markers involved in antibiotic resistance.

Keywords

Antibiotic, Resistance, Genetic Markers.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Allen, H.K., Donato, J., Wang, H.H., Hansen, K.A. Cloud, Davies, J. and Handelsman, J. (2010). Call of the wild: Antibiotic resistance genes in natural environment. Nature Rev. Microbiol., 10: 1038.

  • Anderson, E.S. (1968). The ecology of transferable drug resistance in the enterobacteria. Annu. Rev. Microbiol., 22: 131-180.

  • Cohen, S.N. and Miller, C.A. (1969). Multiple molecular species of circular R-factor DNA isolated from Escherichia coli. Nature, 224: 1273–1277.

  • Cohen, S.N. and Miller, C.A. (1970). Molecular nature of R-factors isolated from Proteus mirabilis and Escherichia coli. J. Mol. Biol., 50 (3): 671–687.

  • Dzidic, S., Suskovic, J and Blazenka, K. (2008). Antibiotic resistance in bacteria. Food Tech. & Biotech., 46(1): 11-21.

  • Gay, P.B. and Gillespie, S.H.. (2005). Antibiotic resistance markers in genetically modified plants: a risk to human health? Lancet Infect Dis., 5(10): 637-646.

  • Guardabassi, L., Petersen, A., Olsen, J.E. and Dalsgaard, A. (1998). Antibiotic resistance in Acinetobacter spp. isolated from sewers receiving waste effluent from a hospital and a pharmaceutical plant. Appl. & Environ. Microbiol., 64: 3499-3502.

  • Hare, P. and Chua, N. (2002). Excision of selectable marker genes from transgenic plants. Nature Biotechnol., 20(6): 575-580.

  • Hayes, J.D. and Wolf, C.R. (1990). Molecular mechanisms of drug resistance. Biochemistry J., 272: 281-295.

  • Kopecko, D.J. and Punch, J.D. (1971). Regulation of R factor replication in Proteus mirabilis. Ann. N.Y.. Acad. Sci., 182: 207-216.

  • Levy, S.B. (1997). Antibiotic resistance: an ecological imbalance. Ciba Foundation Symposium 207: 1-9.

  • Nishioka, T., Mitani, M. and Clowes, R.C. (1969). Composite circular forms of R-factor deoxvribonucleic acid molecules. J. Bacteriol., 97: 376-385.

  • Normak, B.K. and Normak, S. (2002). Evolution and spread of antibiotic resistance. J. Internal Medicine, 252: 91-106.

  • Rownd, R. (1969). Replication of a bacterial episome under relaxed control. J Mol Biol., 28: 44(3): 387–402.

  • Rownd, R. and Mickel, S. (1971). Dissociation and reassociation of RTF and r-determinant of the R-factor NR1 in Proteus mirabilis. Nature New Biol., 234 (45): 40–43.

  • Salyers, A.A and Amabile-Cuevas, C.F. (1997). Why are antibiotic resistance genes so resistant to elimination? Antimicrobial Agents & Chemotherapy, 41(11): 2321-2325.

  • Sharp, P.A., Davidson, N.D. and Cohen, S.N. (1971). Fed. Proc., 30, 1054.

  • Silver, R.P. and Falkow, S. (1970). Specific labeling and physical characterization of R-factor deoxyribonucleic acid in Escherichia coli. J. Bacteriol., 104: 331-339.

  • Watanabe, T. (1971).The problems of drug-resistant pathogenic bacteria. The origin of R factors. Ann N. Y. Acad. Sci., 182: 126–140.


Abstract Views: 323

PDF Views: 0




  • Genetic Markers of Antibiotic Resistance

Abstract Views: 323  |  PDF Views: 0

Authors

I. Sophia
Division of Bacteriology and Mycology, Indian Veterinary Research Institute, Izatnagar, Bareilly (U.P.), India
R. Santhamani
Division of Virology, Indian Veterinary Research Institute, Izatnagar, Bareilly (U.P.), India

Abstract


The failure of antibiotic therapy in human and veterinary medicine has called the world community into a threatening situation. Various measures have been by policy makers across the globe to combat the issue of antimicrobial resistance. The massive problem of therapeutic failure has microelements as its source. This minireview discusses about the genetic markers involved in antibiotic resistance.

Keywords


Antibiotic, Resistance, Genetic Markers.

References