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Syntheses and Anti-Inflammatory Actvity of Diphenyl-2, 2'-Dicarboxylic Acid and its Metal Complexes
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Diphenyl amine-2,2'-dicarboxylic acid and its Cu(II), Ni(II), Co(II) and Zn(II) complexes have been synthesized and characterized by their elemental analyses, molecular weight determination, molar conductance, infrared and electronic spectra and magnetic measurements. The Zinc complex was tested by different methods for anti-inflammatory activity. It was found to be equipotent to Naproxen and Ibuprofen, though in higher dosed.
Keywords
Metal Complex, NSAID’s, Prostaglandins, Anti Inflammatory Agent.
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