Asian Journal of Pharmaceutical Analysis

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Synthesis, Characterization and Antimicrobial Activity of Co(II), Ni(II), Cu(II) and Zn(II) Complexes N- O- S Donor Ligands


Affiliations
1 Department of Chemistry, Agra College, Agra, U.P, India
2 B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India
     

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The Co(II), Ni(II), Cu(II) and Zn(II) complexes of the composition 1:1:1 molar ratio, (ML1L2) (where L1=diphenylamine-2-mercapto-2-carboxylic acid and L2=2-furyl glyoxalanthranilic acid have been synthesized and characterized by elemental analyses, H-NMR, IR, electronic spectral data and magnetic susceptibility measurements. The synthesized ligands and their metal complexes were screened for their antimicrobial activity against two bacteria Staphylococcus aureus (gram +ve) and Escherichia coli (gram -ve) and two fungi Aspergillus niger and Apergillus flavus by Serial Dilution Method. Metal complexes are more active than their ligands.

Keywords

Mixed Ligand Complexes, Antimicrobial Activity.
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  • Synthesis, Characterization and Antimicrobial Activity of Co(II), Ni(II), Cu(II) and Zn(II) Complexes N- O- S Donor Ligands

Abstract Views: 255  |  PDF Views: 2

Authors

Vinita Gupta
Department of Chemistry, Agra College, Agra, U.P, India
Sanchita Singh
Department of Chemistry, Agra College, Agra, U.P, India
Y. K. Gupta
B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India

Abstract


The Co(II), Ni(II), Cu(II) and Zn(II) complexes of the composition 1:1:1 molar ratio, (ML1L2) (where L1=diphenylamine-2-mercapto-2-carboxylic acid and L2=2-furyl glyoxalanthranilic acid have been synthesized and characterized by elemental analyses, H-NMR, IR, electronic spectral data and magnetic susceptibility measurements. The synthesized ligands and their metal complexes were screened for their antimicrobial activity against two bacteria Staphylococcus aureus (gram +ve) and Escherichia coli (gram -ve) and two fungi Aspergillus niger and Apergillus flavus by Serial Dilution Method. Metal complexes are more active than their ligands.

Keywords


Mixed Ligand Complexes, Antimicrobial Activity.