Asian Journal of Pharmaceutical Analysis

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A New Analytical Method Development and Validation for Estimation of Ciprofloxacin in Bulk and Pharmaceutical Dosage Form


Affiliations
1 Venkateswara Institute of Pharmaceutical Seinces, Cherlapally, Nalgonda -508001, India
2 Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist. -501510, India
     

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A sensitive, precise, accurate and simple UV spectrophotometric method has been developed for estimation of ciprofloxacin in bulk and pharmaceutical dosage form. The drug shows maximum absorbance at 273 nm (max). The linearity was observed in the concentration range of 5-50mcg/ml. The proposed method has been applied successfully to the analysis of cited drug in pharmaceutical formulation. Recovery study was performed to confirm the accuracy of the method. The method was validated as per ICH guide lines.

Keywords

Estimation, Ciprofloxacin, UV Spectrophotometer.
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  • A New Analytical Method Development and Validation for Estimation of Ciprofloxacin in Bulk and Pharmaceutical Dosage Form

Abstract Views: 451  |  PDF Views: 0

Authors

Manoranjan Sabat
Venkateswara Institute of Pharmaceutical Seinces, Cherlapally, Nalgonda -508001, India
Sharada Nalla
Venkateswara Institute of Pharmaceutical Seinces, Cherlapally, Nalgonda -508001, India
Venkateswarlu Goli
Venkateswara Institute of Pharmaceutical Seinces, Cherlapally, Nalgonda -508001, India
Sravan Prasad Macherla
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist. -501510, India
Praveena Kumari Matta
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist. -501510, India
S. Madhu Chandaka
Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist. -501510, India

Abstract


A sensitive, precise, accurate and simple UV spectrophotometric method has been developed for estimation of ciprofloxacin in bulk and pharmaceutical dosage form. The drug shows maximum absorbance at 273 nm (max). The linearity was observed in the concentration range of 5-50mcg/ml. The proposed method has been applied successfully to the analysis of cited drug in pharmaceutical formulation. Recovery study was performed to confirm the accuracy of the method. The method was validated as per ICH guide lines.

Keywords


Estimation, Ciprofloxacin, UV Spectrophotometer.