Colorimetric Estimation of Secnidazole in Bulk and Tablet Dosage Form

A new simple, sensitive and precise visible spectrophotometric method has been developed for the determination of Secnidazole in bulk and in pharmaceutical formulation. This method is based on the reduction of secnidazole, in the presence of 4N Hydrochloric acid and ethanol to form yellow colored chromogen. Which was estimated at an absorption maximum of 477.5 nm. This method has the linearity in the concentration range of 100-500μg/ml. This method is statistically evaluated for efficacy.