Asian Journal of Pharmaceutical Research

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Dendrimer:A Review


Affiliations
1 Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, Maharashtra, India
2 Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, Maharashtra, India
     

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Dendrimers are a interesting class of synthetic macromolecules having highly branched, three dimensional, nanoscale architecture with very low polydispersity and high functionality. These features have made their application in nanotechnology, pharmaceutical and medicinal chemistry particularly attractive. This review article is focused on different synthetic strategies used in dendrimer synthesis at commercial and laboratory scale. These synthetic strategies includes their own advantages and disadvantages. This review will cover divergent (from core to surface) and convergent (from surface to core) approaches used in dendrimer synthesis and the problems associated with these synthetic strategies. This article also covers the important applications of dendrimers in the field of pharmaceutical sciences. This data of review is collected from various articles, research papers and patents available on dendrimers.
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  • Dendrimer:A Review

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Authors

Sheetal B. Gondkar
Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, Maharashtra, India
Shalaka P. Rasal
Department of Pharmaceutics, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, Maharashtra, India
Ravindra B. Saudagar
Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, Maharashtra, India

Abstract


Dendrimers are a interesting class of synthetic macromolecules having highly branched, three dimensional, nanoscale architecture with very low polydispersity and high functionality. These features have made their application in nanotechnology, pharmaceutical and medicinal chemistry particularly attractive. This review article is focused on different synthetic strategies used in dendrimer synthesis at commercial and laboratory scale. These synthetic strategies includes their own advantages and disadvantages. This review will cover divergent (from core to surface) and convergent (from surface to core) approaches used in dendrimer synthesis and the problems associated with these synthetic strategies. This article also covers the important applications of dendrimers in the field of pharmaceutical sciences. This data of review is collected from various articles, research papers and patents available on dendrimers.