A Review on Irbesartan Co-Administered with Atorvastatin for the Treatment of Cardiac Risk

Hypertension and Hypercholesterolemia are a major public health problem in the developed Countries in recently Hypertension and hypercholesterolemia are frequently treated with antihypertensive drugs like calcium-channels blockers, angiotensin-converting enzyme inhibitors, and angiotensin II type 1 (AT1) receptor blockers, and statins. Irbesartan is Angiotensin II receptor type 1 antagonist and widely used in treatment of hypertension condition. Atorvastatin is HMG CoA reductase inhibitor and widely used in treatment of hyperlipidaemias condition. Combination of irbesartan and atorvastatin is used to treatment of cardiovascular diseases like hypertension and hyperlipidemias, so this combination therapy gives antihypertensive and antilipidemic treatment for condition of coronary artery diseases.