A Comparative Analysis of Antibacterial Activity of Withania somnifera Root Extract with Commercial Antibiotics

Antibiotics play a major role in clinical medicine in eradicating pathogens. Unfortunately, excessive/inappropriate use of antibiotics has contributed to the spread of important clinical and public health problems of antibiotics resistance. The present study aimed to examine a comparative analysis of the antibacterial efficacy of ethanol and methanol ischolar_main extracts of W. somnifera with commercial antibiotics against the bacterial strains. The ethanol and methanol ischolar_main extracts of W. somnifera found to show equalent/potent antibacterial activity against the bacterial strains as compared to antibiotic discs. Methanol ischolar_main extract of W. somnifera showed an effective antibacterial activity might be due to presence of numerous bioactive compounds. Thus, there is a tremendous need for future research to provide better evidence, to address the isolation and characterization of these bioactive components of methanol ischolar_main extract of W. somnifera responsible for the antibacterial activity, offer an ecologically and economically safe drug compared to commercial antibiotics.