Asian Journal of Pharmaceutical Research

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Synergic Interaction between Antibiotics and the Artificial Sweeteners Xylitol and Sorbitol against Pseudomonas aeruginosa Biofilms


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1 Department of Microbiology and Immunology, Zagazig University, Zagazig, Egypt
     

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Biofilm-associated infections are persistent and difficult to treat due to the multifactorial antimicrobial resistance. Sugar alcohols have a significant inhibitory effect on dental biofilms. They can reduce the amount of dental plaque and the extracellular polysaccharide (glucans) and intracellular matrix production. The interference with the production of glucans could decrease the extracellular matrix component of mixed oral biofilms.
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  • Synergic Interaction between Antibiotics and the Artificial Sweeteners Xylitol and Sorbitol against Pseudomonas aeruginosa Biofilms

Abstract Views: 240  |  PDF Views: 1

Authors

Hisham A. Abbas
Department of Microbiology and Immunology, Zagazig University, Zagazig, Egypt
Fathy M. Serry
Department of Microbiology and Immunology, Zagazig University, Zagazig, Egypt
Eman M. EL-Masry
Department of Microbiology and Immunology, Zagazig University, Zagazig, Egypt

Abstract


Biofilm-associated infections are persistent and difficult to treat due to the multifactorial antimicrobial resistance. Sugar alcohols have a significant inhibitory effect on dental biofilms. They can reduce the amount of dental plaque and the extracellular polysaccharide (glucans) and intracellular matrix production. The interference with the production of glucans could decrease the extracellular matrix component of mixed oral biofilms.