Asian Journal of Pharmaceutical Research

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Corona Virus Disease (COVID-19): A past and Present Prospective


Affiliations
1 Department of Pharmaceutics, Sandip Institute of Pharmacy, Nashik, India
2 Department of Pharmaceutics, MET’s Institute of Pharmacy, Adgaon Nashik, India
3 Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
4 Department of Pharmaceutical Chemistry, Matoshri College of Pharmacy, Eklahare, Nashik, India
     

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Background: Corona virusis identified since 2002 and from seven strain severe acute respiratory syndrome corona virus corona virus causes severity in patients and then in December 2019, an outbreak of severe acute respiratory syndrome Corona virus 2 infection ensued in Wuhan, China and spread crosswise China and beyond. On February 12, 2020, WHO officially named the disease caused by the novel Corona virusas Corona virus Disease 2019 (COVID-19). Main Text: This form of virus comes up its growth when expose to any of the naturally expose material and the precaution for this is only single oriented, that is keeping yourself hygienic by washing your hands by utilizing high grade sanitizer. The literature survey revealed that Corona virus strain mainly severe acute respiratory syndrome corona virus and middle east respiratory syndrome Corona virus and human corona virus preserve on various surfaces like metal, glass or plastic for about 9 days but inactivation of virus by utilizing various virucide. On infection, the virus has a surge of proinflammatory cytokines and chemokines, which do damage to lung tissue, deterioration of lung function, and then eventually go to lung failure. Drug discovery against the virus is a challenging line of work owing to frequent recombination events. The evolution of a vaccine is another significant facet. Research is in ongoing stage to develop vaccine and medicines for COVID 19. In such circumstances, other system of medicineis widely used, like Allopathy, Ayurveda and Unani. Unani system of medicine utilized some measures for health protection during epidemics. In Unani medicine, during an epidemic, apart from isolation and quarantine, three measures are of utmost importance, impurification of surroundings using certain herbal drugs as fumigants or sprays, health promotion and immune-modulation, and use of health-protecting drugs and symptom-specific drugs. Conclusion: We require more structural biological details which put up rush up the drug or vaccine development process against corona virus. Thus, objective of this follow-up article is to focus on past to present perspective on corona virus pandemic.

 


Keywords

Novel Corona virus, Severe Acute Respiratory syndrome (SARS) corona virus, Middle East Respiratory syndrome (MERS), replication, life cycle, Vaccine
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  • Corona Virus Disease (COVID-19): A past and Present Prospective

Abstract Views: 119  |  PDF Views: 0

Authors

Swati G. Talele
Department of Pharmaceutics, Sandip Institute of Pharmacy, Nashik, India
Eknath D. Ahire
Department of Pharmaceutics, MET’s Institute of Pharmacy, Adgaon Nashik, India
Khemchand R. Surana
Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
Vijayraj N. Sonawane
Department of Pharmaceutical Chemistry, Shreeshakti Shaikshanik Sanstha, Divine College of Pharmacy, Satana, Nashik, India
Gokul S. Talele
Department of Pharmaceutical Chemistry, Matoshri College of Pharmacy, Eklahare, Nashik, India

Abstract


Background: Corona virusis identified since 2002 and from seven strain severe acute respiratory syndrome corona virus corona virus causes severity in patients and then in December 2019, an outbreak of severe acute respiratory syndrome Corona virus 2 infection ensued in Wuhan, China and spread crosswise China and beyond. On February 12, 2020, WHO officially named the disease caused by the novel Corona virusas Corona virus Disease 2019 (COVID-19). Main Text: This form of virus comes up its growth when expose to any of the naturally expose material and the precaution for this is only single oriented, that is keeping yourself hygienic by washing your hands by utilizing high grade sanitizer. The literature survey revealed that Corona virus strain mainly severe acute respiratory syndrome corona virus and middle east respiratory syndrome Corona virus and human corona virus preserve on various surfaces like metal, glass or plastic for about 9 days but inactivation of virus by utilizing various virucide. On infection, the virus has a surge of proinflammatory cytokines and chemokines, which do damage to lung tissue, deterioration of lung function, and then eventually go to lung failure. Drug discovery against the virus is a challenging line of work owing to frequent recombination events. The evolution of a vaccine is another significant facet. Research is in ongoing stage to develop vaccine and medicines for COVID 19. In such circumstances, other system of medicineis widely used, like Allopathy, Ayurveda and Unani. Unani system of medicine utilized some measures for health protection during epidemics. In Unani medicine, during an epidemic, apart from isolation and quarantine, three measures are of utmost importance, impurification of surroundings using certain herbal drugs as fumigants or sprays, health promotion and immune-modulation, and use of health-protecting drugs and symptom-specific drugs. Conclusion: We require more structural biological details which put up rush up the drug or vaccine development process against corona virus. Thus, objective of this follow-up article is to focus on past to present perspective on corona virus pandemic.

 


Keywords


Novel Corona virus, Severe Acute Respiratory syndrome (SARS) corona virus, Middle East Respiratory syndrome (MERS), replication, life cycle, Vaccine

References