Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

An Overview about Medicinal Chemistry and Pharmaceutical Applications of 2, 4-Imidazolidinone and its Derivatives


Affiliations
1 Government Engineering College, Valsad, Near Sanskar Kendra, Tithal Road, Valsad-396001, India
2 B.K.M. Science College, Near Sanskar Kendra, Tithal Road, Valsad-396001, India
     

   Subscribe/Renew Journal


2,4-imidazolidinedione is a heterocyclic compound commonly well known as Hydantoin. Starting from its first synthesis it is found interesting among the medicinal and pharmaceutical chemists. In this review article we have briefly described different methods of synthesis with the help of some name reactions like Buchere-Bergs reaction and Diels-Alder reaction. It is found that this molecule is synthesized with three substitutions where different organic reactive groups imports different pharmacological properties in the molecules of hydantoin derivatives. The broad pharmacological activities of 2,4-imidazolidinedione is also discussed in this work for more than 16 dieses. This review article will be very good useful for scholars and scientists to explore more possibilities with other derivatives using the methods given in this review paper.

Keywords

Hydantoin, Allantoin, Imidazolidinedione, Heterocyclic, Phenyl Urea.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 233

PDF Views: 0




  • An Overview about Medicinal Chemistry and Pharmaceutical Applications of 2, 4-Imidazolidinone and its Derivatives

Abstract Views: 233  |  PDF Views: 0

Authors

Bhadreshkumar R. Sudani
Government Engineering College, Valsad, Near Sanskar Kendra, Tithal Road, Valsad-396001, India
Vikas A. Desai
B.K.M. Science College, Near Sanskar Kendra, Tithal Road, Valsad-396001, India

Abstract


2,4-imidazolidinedione is a heterocyclic compound commonly well known as Hydantoin. Starting from its first synthesis it is found interesting among the medicinal and pharmaceutical chemists. In this review article we have briefly described different methods of synthesis with the help of some name reactions like Buchere-Bergs reaction and Diels-Alder reaction. It is found that this molecule is synthesized with three substitutions where different organic reactive groups imports different pharmacological properties in the molecules of hydantoin derivatives. The broad pharmacological activities of 2,4-imidazolidinedione is also discussed in this work for more than 16 dieses. This review article will be very good useful for scholars and scientists to explore more possibilities with other derivatives using the methods given in this review paper.

Keywords


Hydantoin, Allantoin, Imidazolidinedione, Heterocyclic, Phenyl Urea.