Asian Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Development and Evaluation of Dashmula Plants of Ayurveda


Affiliations
1 Dr. K.N. Modi, Institute of Pharmaceutical Education and Research, Modinagar, Uttar Pradesh - 201204, India
     

   Subscribe/Renew Journal


Dashmool tablet is made with various ingredients in the formulation composition.It is a versatile indigenous drug, claimed by Ayurvedic system of medicine to be highly efficacious in the treatment of Rheumatism arthritis, inflammation. The two important Pharmacological properties of Dashmool are immunomodulator and febrifugal properties. Dashmool which is used traditionally for treatment of number of diseases like jaundice, rheumatism, puerperal forever ,paralysis, oedema, filarial and post natal care to avoid secondary complications. It provides general support to the body during period of Influenza, cough, cold, neuralgia and headaches. It is used as dietary supplement .It combines synergistic benefit of dashmool with other herbs. The present study involved the preparation of dashmool herbal tablet. Tablets were prepared by direct compression Dashmool tablet each weighing 1160 mg containing 250 mg of active ingredient of drug formulated. Tablets were evaluated for Disintegration, Hardness, Friability, Description, Uniformity of weight, Quantitative Standards, Physicochemical parameters (e.g Total ash %), Acid Insoluble ash, Alcohol soluble extract,water soluble extract.

Keywords

Total Ash, Alcohol Soluble Extractive, Disintegration.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Kritikar KR et al, Basu BD .Indian medicinal plants with illustrations, 2nd edition, vol-3. Dehra Dun: Oriental Enterprises; 2001; 1061.

  • Sharma PV et al. Dravyaguna-Vijnan, vol-II. Varanasi: Chaukhamba Bharti .Academy; 1992. p. 820.

  • Govindarajan R et al, Singh DP, Rawat AKS. J Pharm Biomed Anal 2007; 43:527.

  • Ramchandra NS et al, Vavhal RR, Kulkarni CJ. Effect of Dashmool churna, Varunadi Kwath and Kanchanar Guggul on uterine fibroid. Ayurlog: National Journal of Research in Ayurved Science 2015; 3: 1-5.

  • Meena AK et al, Rao MM, Kandale A, Sannd R, Kiran, Niranjan U, Yadav AK. Standardisation of Desmodium gangeticum- A Tradition Ayurvedic Plant. Drug Invention Today 2010; 2: 182-184.

  • Jabbar S et al , Mahmud T, Shahabuddin M, Choudhuri K, Bijon K. Bioactivity Studies of the Individual Ingredients of the Dashmularishta. Pak J Pharm Sci 201 4; 17: 9-17.

  • Sekar S et al, Mariappan S. Traditionally fermented biomedicines, arishtas and asavas from Ayurveda. Indian J Trad Knowl 2008; 7: 548-556.

  • Nash R et al. Introduction. In: R. A. Nash, A. H. Wachter, Pharmaceutical Process Validation, Vol.129, An International 3rd Edition, Revised and Expanded, Marcel Dekker, New York 2003, 17-18. 2.

  • Lieberman H, et al Lachman L, Joseph B. Schwartz, Pharmaceutical Dosage Forms Tablets, second edition, volume 3, Marcel Dekker. Inc, New York, 1990, 417-447.

  • Ayurvedic Pharmacopoeia of India Part 2, Volume 2, First Edition (Formulations) Government of India, Ministry of Health and Family Welfare, Department of Ayurveda, Yoga and Naturopathy, Unani, Sidha and Homoeopathy (Ayush) New Delhi.

  • Lachman leon et al, Liberman Herbert A. Theory and Practice of Industrial Pharmacy, edn. 2009, p: 293-294.

  • Leon Lachman et al, Liberman Herbert A. Drug Dosage Form and Drug Delivery System Design. 2009:90-91.

  • Patil J et al, Chandrashekhar K, Gopal V. Formulation, design and evaluation of orally disintegrating tablets of Loratadine using direct compression process. International Journal of Pharma and Bio sciences 2011; 2:389-400.

  • Ayurvedic Pharmacopoeia of India Part 2, Volume 2, First Edition (Formulations) Government of India, Ministry of Health and Family Welfare, Department of Ayurveda, Yoga and Naturopathy, Unani, Sidha and Homoeopathy (Ayush) New Delhi.

  • Yamsani MR et al. Factors influencing the Design and Performance of Oral Sustained/Controlled Release Dosage Forms. International Journal of Pharmaceutical Sciences and Nanotechnology. 2009; 2(3):583-593.

  • Indian Pharmacopoeia 2010, Volume 1, Published By The Indian Pharmacopoeia Commision, Ghaziabad.

  • Remington the Science and Practice of Pharmacy 20th Edition, Lippincott Williams and Wilkins International Student Edition.

  • Jain N K et al, Sharma S N. A Text book of professional pharmacy, Vallabh Prakashan.

  • Remington the Science and Practice of Pharmacy 20th Edition, Lippincott Williams and Wilkins International Student Edition.

  • Larry L et al, Augsburger, Stephen W. Hoag, Pharmaceutical Dosage Forms: Tablets, 3rd Edition, Volume 1- Unit Operations and Mechanical Properties: 173-75.

  • Kumar G et al Dokala, Pallavi C. Direct Compression - An Overview. International Journal of Research in Pharmaceutical and Biomedical Sciences; 2229-3701.

  • Solanki Himanshu K et al Basuri Tarashankar, Thakkar Jalaram H, Patel Chirag A. Recent Advances in Granulation Technology, Volume 5, Article-008.

  • Agrawal Rajesh et al, Yadav Naveen. Pharmaceutical Processing - A Review on Wet Granulation Technology, IJPFR, April-June 2011; 1(1):65-83.

  • 24.Reddy Venkateshwara B et al, K. Navaneetha, Reddy Rashmitha B. Tablet Coating industry point view- A comprehensive review, IJPBSJ 2013;3(1):248-61 . 25. Senem S et al, Imran V. Advantages and Quality Control of Orally Disintegrating Tablets, FABAD J. Pharm. Sci 2009; 34:167-72.

  • Parmar Krutin D et al , Bhatt Nayana M, Pathak Nimish L, Patel Laxmanbhai D An Overview: Aqueous Film Coating Technology on Tablets International Journal of Pharmaceutical and Chemical Sciences, ISSN:2277-5005 .

  • Pawar N, Kogje A et al , Bhondave P, Nagarkar B, Kulkarni O, Harsulkar A , Jagtap S . Comparative Free Radical Scavenging and Anti-Inflammatory Potential of Branded Market Samples of An Ayurvedic Formulation: Dashamoolarishta, International Journal of Pharma and Bio Sciences, ISSN 0975-6299.

  • Vador N et al, Vador B , Hole R . Simple Spectrophotometric Methods for Standardizing Ayurvedic Formulation. Indian J Pharm Sci. 2012; 74(2): 161-163.


Abstract Views: 629

PDF Views: 1




  • Development and Evaluation of Dashmula Plants of Ayurveda

Abstract Views: 629  |  PDF Views: 1

Authors

Yogita Chowdhary
Dr. K.N. Modi, Institute of Pharmaceutical Education and Research, Modinagar, Uttar Pradesh - 201204, India

Abstract


Dashmool tablet is made with various ingredients in the formulation composition.It is a versatile indigenous drug, claimed by Ayurvedic system of medicine to be highly efficacious in the treatment of Rheumatism arthritis, inflammation. The two important Pharmacological properties of Dashmool are immunomodulator and febrifugal properties. Dashmool which is used traditionally for treatment of number of diseases like jaundice, rheumatism, puerperal forever ,paralysis, oedema, filarial and post natal care to avoid secondary complications. It provides general support to the body during period of Influenza, cough, cold, neuralgia and headaches. It is used as dietary supplement .It combines synergistic benefit of dashmool with other herbs. The present study involved the preparation of dashmool herbal tablet. Tablets were prepared by direct compression Dashmool tablet each weighing 1160 mg containing 250 mg of active ingredient of drug formulated. Tablets were evaluated for Disintegration, Hardness, Friability, Description, Uniformity of weight, Quantitative Standards, Physicochemical parameters (e.g Total ash %), Acid Insoluble ash, Alcohol soluble extract,water soluble extract.

Keywords


Total Ash, Alcohol Soluble Extractive, Disintegration.

References