Asian Journal of Pharmacy and Technology

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Mucormycosis: A Lethal Disease


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1 Gurukrupa Institute of Pharmacy [Degree] Malipargaon, Phata, Majalgaon, Dist: Beed, 431129, India
     

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Mucormycosis is an emerging infection associated with high mortality. These fungi are very common molds to which exposure is probably quite frequent, still, clinical disease is rare and affects severely immunocompromised patients or patients with diabetes mellitus. Mucormycosis is manifested by a wide variety of syndromes, devastating rhino-orbitalcerebral and pulmonary infections are the major presentation. The diagnosis of mucormycosis relies upon the identification of organisms in tissue, however culture often yields no growth. Mucormycosis are serious infections caused by filamentous fungi of the order Mucorales. Mucormycosis is a life-threatening infection caused by fungi of the order Mucorales. Recent reclassification has abolished the order Zygomycetes and placed the order Mucorales in the subphylum Mucormycotina. We report five cases of mucormycosis of patients hospitalized, In 2021. They were 4 males and 1 female, mean age 60 years. All patients were treated with amphotericin B and posiconazole.

Keywords

Mucormycosis, Amphotericin B, Posiconazole, Fungi
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  • Mucormycosis: A Lethal Disease

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Authors

Pawan N. Karwa
Gurukrupa Institute of Pharmacy [Degree] Malipargaon, Phata, Majalgaon, Dist: Beed, 431129, India
Jyoti K. Soundarmal
Gurukrupa Institute of Pharmacy [Degree] Malipargaon, Phata, Majalgaon, Dist: Beed, 431129, India
Pallavi S. Shinde
Gurukrupa Institute of Pharmacy [Degree] Malipargaon, Phata, Majalgaon, Dist: Beed, 431129, India
Swapna R. Jalde
Gurukrupa Institute of Pharmacy [Degree] Malipargaon, Phata, Majalgaon, Dist: Beed, 431129, India

Abstract


Mucormycosis is an emerging infection associated with high mortality. These fungi are very common molds to which exposure is probably quite frequent, still, clinical disease is rare and affects severely immunocompromised patients or patients with diabetes mellitus. Mucormycosis is manifested by a wide variety of syndromes, devastating rhino-orbitalcerebral and pulmonary infections are the major presentation. The diagnosis of mucormycosis relies upon the identification of organisms in tissue, however culture often yields no growth. Mucormycosis are serious infections caused by filamentous fungi of the order Mucorales. Mucormycosis is a life-threatening infection caused by fungi of the order Mucorales. Recent reclassification has abolished the order Zygomycetes and placed the order Mucorales in the subphylum Mucormycotina. We report five cases of mucormycosis of patients hospitalized, In 2021. They were 4 males and 1 female, mean age 60 years. All patients were treated with amphotericin B and posiconazole.

Keywords


Mucormycosis, Amphotericin B, Posiconazole, Fungi

References