Asian Journal of Pharmacy and Technology

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A Compendious Review on Biodegradable Polymeric Nanoparticles


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1 Yashoda Shikshan Prasarak Mandal, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe NH4, Satara. 415011, Maharashtra, India
     

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Polymeric nanoparticles (NPs) are among the eminently designed organic nanomedicine. There is a lot of elation about polymeric NPs' potential to revolutionize modern medicine. Particle size, morphology, material selection, and processing methods are all being studied to synthesize the perfect nanosystem for effectual and precisely target bioactive. PNPs have the ability to significantly elevate the potency of therapeutic medication by allowing for targeted distribution to a specific location. Drug delivery techniques such as conjugation and trapping of medicines, prodrugs, stimuli-responsive systems, imaging modalities, and theranostics all use polymeric NPs. The review focuses on the array of existing approaches for the producing of polymeric nanoparticles. We want to draw attention to several natural and synthetic biodegradable polymers. Polymers' physiochemical properties can be tweaked to provide distribution through several biological barriers in order to reach distinct organs or cells. The use of biodegradable polymers as nanocarriers is particularly appealing since these materials can be tailored to degrade in physiological system. Additionally, in the next part, the characterization methods for this type of nanoparticles are discussed.

Keywords

Targeted Delivery, Controlled Manner, Biodegradable Polymer, Nanocarrier, Polymeric Nanoparticles
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  • A Compendious Review on Biodegradable Polymeric Nanoparticles

Abstract Views: 172  |  PDF Views: 0

Authors

Shivani Deshmukh
Yashoda Shikshan Prasarak Mandal, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe NH4, Satara. 415011, Maharashtra, India
Bharati Chaudhari
Yashoda Shikshan Prasarak Mandal, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe NH4, Satara. 415011, Maharashtra, India
Atish Velhal
Yashoda Shikshan Prasarak Mandal, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe NH4, Satara. 415011, Maharashtra, India
Vivekkumar Redasani
Yashoda Shikshan Prasarak Mandal, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe NH4, Satara. 415011, Maharashtra, India

Abstract


Polymeric nanoparticles (NPs) are among the eminently designed organic nanomedicine. There is a lot of elation about polymeric NPs' potential to revolutionize modern medicine. Particle size, morphology, material selection, and processing methods are all being studied to synthesize the perfect nanosystem for effectual and precisely target bioactive. PNPs have the ability to significantly elevate the potency of therapeutic medication by allowing for targeted distribution to a specific location. Drug delivery techniques such as conjugation and trapping of medicines, prodrugs, stimuli-responsive systems, imaging modalities, and theranostics all use polymeric NPs. The review focuses on the array of existing approaches for the producing of polymeric nanoparticles. We want to draw attention to several natural and synthetic biodegradable polymers. Polymers' physiochemical properties can be tweaked to provide distribution through several biological barriers in order to reach distinct organs or cells. The use of biodegradable polymers as nanocarriers is particularly appealing since these materials can be tailored to degrade in physiological system. Additionally, in the next part, the characterization methods for this type of nanoparticles are discussed.

Keywords


Targeted Delivery, Controlled Manner, Biodegradable Polymer, Nanocarrier, Polymeric Nanoparticles

References