Asian Journal of Research in Chemistry

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Evaluation of In Vitro Nitric Oxide Scavenging Activity of Medicinal Plant-Ehretia laevis


Affiliations
1 Dr. T. R. Ingle Research Laboratory, Department of Chemistry, S. P. College, Tilak Road, Pune–411 030, Maharashtra, India
2 Yashwantrao Mohite College, Bharati Vidyapeeth, Deemed University, Pune, Maharashtra, India
     

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Ehretia laevis, from the family Boraginaceae is an important medicinal plant. All parts are widely used in medicines. Present study reports in vitro antioxidant activity of ethanol extract of leaves and stem of Ehretia laevis. The study was further extended for fractionation of leaves extract in methanol. Those various activities were compared to standard antioxidant such as ascorbic acid. The comparison of antioxidant activity of stem and leaves, prepared in 80 % ethanol, reveals that activity of leaves is higher than that of stem. Methanol extract, prepared at room temperature, along with its fractions indicates activity. As antioxidant therapy is found to be useful in complicated disease status related with free radical activity, the present study might be extended for the formulation and evaluation of different antioxidant herbal dosage forms.

Keywords

Ehretia laevis, Boraginaceae, Antioxidant, Nitric Oxide Scavenging Activity.
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  • Evaluation of In Vitro Nitric Oxide Scavenging Activity of Medicinal Plant-Ehretia laevis

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Authors

Rasika C. Torane
Dr. T. R. Ingle Research Laboratory, Department of Chemistry, S. P. College, Tilak Road, Pune–411 030, Maharashtra, India
Vaishali B. Adsul
Yashwantrao Mohite College, Bharati Vidyapeeth, Deemed University, Pune, Maharashtra, India
Chandrakant D. Shendkar
Yashwantrao Mohite College, Bharati Vidyapeeth, Deemed University, Pune, Maharashtra, India
Nirmala R. Deshpande
Dr. T. R. Ingle Research Laboratory, Department of Chemistry, S. P. College, Tilak Road, Pune–411 030, Maharashtra, India

Abstract


Ehretia laevis, from the family Boraginaceae is an important medicinal plant. All parts are widely used in medicines. Present study reports in vitro antioxidant activity of ethanol extract of leaves and stem of Ehretia laevis. The study was further extended for fractionation of leaves extract in methanol. Those various activities were compared to standard antioxidant such as ascorbic acid. The comparison of antioxidant activity of stem and leaves, prepared in 80 % ethanol, reveals that activity of leaves is higher than that of stem. Methanol extract, prepared at room temperature, along with its fractions indicates activity. As antioxidant therapy is found to be useful in complicated disease status related with free radical activity, the present study might be extended for the formulation and evaluation of different antioxidant herbal dosage forms.

Keywords


Ehretia laevis, Boraginaceae, Antioxidant, Nitric Oxide Scavenging Activity.