Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Development of UV Spectrophotometric Methods for Simultaneous Estimation of Atorvastatin and Telmisartan in Combined Dosage Form Using Simultaneous Equation Method


Affiliations
1 J. L. Chaturvedi College of Pharmacy, Electronic Zone Building MIDC, Hingna Road, Nagpur, Maharashtra, Pin 400016, India
     

   Subscribe/Renew Journal


A new, simple, rapid and novel spectrophotometric method has been developed for simultaneous estimation of Atorvastatin and Telmisartan For this, simultaneous equation method is used. The method involved measurement of absorbance at two wavelengths, 246.20 nm and 290 nm, _ max of Atorvastatin and Telmisartan respectively. Beer's law obeyed in concentration range of 5-30 μg/ mL and 5-30 μg/ mL for Atorvastatin and Telmisartan respectively. The proposed method is recommended for routine analysis since it is rapid, simple, accurate and also sensitive and specific by no heating and no

organic solvent extraction. This paper describes the development and validation of UV spectroscopic method for Simultaneous estimation of Atorvastatin and Telmisartan in combined solid dosage form.


Keywords

Atorvastatin, Telmisartan, Simultaneous Equation Method.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 236

PDF Views: 0




  • Development of UV Spectrophotometric Methods for Simultaneous Estimation of Atorvastatin and Telmisartan in Combined Dosage Form Using Simultaneous Equation Method

Abstract Views: 236  |  PDF Views: 0

Authors

L. T. Thote
J. L. Chaturvedi College of Pharmacy, Electronic Zone Building MIDC, Hingna Road, Nagpur, Maharashtra, Pin 400016, India
A. R. Umarkar
J. L. Chaturvedi College of Pharmacy, Electronic Zone Building MIDC, Hingna Road, Nagpur, Maharashtra, Pin 400016, India
D. R. Chaple
J. L. Chaturvedi College of Pharmacy, Electronic Zone Building MIDC, Hingna Road, Nagpur, Maharashtra, Pin 400016, India

Abstract


A new, simple, rapid and novel spectrophotometric method has been developed for simultaneous estimation of Atorvastatin and Telmisartan For this, simultaneous equation method is used. The method involved measurement of absorbance at two wavelengths, 246.20 nm and 290 nm, _ max of Atorvastatin and Telmisartan respectively. Beer's law obeyed in concentration range of 5-30 μg/ mL and 5-30 μg/ mL for Atorvastatin and Telmisartan respectively. The proposed method is recommended for routine analysis since it is rapid, simple, accurate and also sensitive and specific by no heating and no

organic solvent extraction. This paper describes the development and validation of UV spectroscopic method for Simultaneous estimation of Atorvastatin and Telmisartan in combined solid dosage form.


Keywords


Atorvastatin, Telmisartan, Simultaneous Equation Method.