Asian Journal of Research in Chemistry

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Spectrophotometric Determination of Mosapride Citrate in Pharmaceutical Formulations


Affiliations
1 Department of Chemistry, Government College for Men, Kurnool-518002, India
2 Department of Chemistry, S. K. University, Anantapur-515003, India
3 Department of Chemistry, S.B.S.Y.M. Degree College, Kurnool-518218, India
     

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A simple spectrophotometric method has been developed for the estimation of mosapride in tablet formulations. The method is based on the formation of a orange coloured azo product by the diazotization of mosapride followed by a coupling reaction with resorcinol. The absorbance of orange coloured solution is measured at 470 nm against reagent blank. Beer's law is obeyed in the concentration of 20-100 μg/ml of drug. The method is successfully employed for the determination of mosapride in tablets formulations.

Keywords

Spectrophotometry, Mosapride Citrate, Resorcinol, Diazotization Formulations.
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  • Spectrophotometric Determination of Mosapride Citrate in Pharmaceutical Formulations

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Authors

M. Purushotham Reddy
Department of Chemistry, Government College for Men, Kurnool-518002, India
P. Ravindra Reddy
Department of Chemistry, S. K. University, Anantapur-515003, India
N. Rami Reddy
Department of Chemistry, S.B.S.Y.M. Degree College, Kurnool-518218, India

Abstract


A simple spectrophotometric method has been developed for the estimation of mosapride in tablet formulations. The method is based on the formation of a orange coloured azo product by the diazotization of mosapride followed by a coupling reaction with resorcinol. The absorbance of orange coloured solution is measured at 470 nm against reagent blank. Beer's law is obeyed in the concentration of 20-100 μg/ml of drug. The method is successfully employed for the determination of mosapride in tablets formulations.

Keywords


Spectrophotometry, Mosapride Citrate, Resorcinol, Diazotization Formulations.