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Green Synthesis of Quinoxaline Derivatives


Affiliations
1 Department of Chemistry, Rajshri Shahu Mahavidhyalaya, Latur, India
2 Department of Chemistry, K M C College, Khopoli, Dist Raigad, India
3 Department of Chemistry, S. M. P. College, Murum, Omerga, Dist: Osmanabad, India
4 Department of Chemistry, Shivneri Mahavidhyalaya, Shirur, Anantpal Dist Latur, India
     

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The objective of present research work is to provide green technique for synthesis of 2,3-diphenyl quinoxaline. Quinoxaline derivatives are well known in the pharmaceutical industry. A simple, highly efficient and green procedure for the condensation of α-phenylenediamine with α-diketones in the presence of catalytic quantity of iodine. Thevery mild reaction conditions, the high yields of the products, and the use of water as solvent make this methodology an efficient and green route for synthesis of quinoxalines derivatives.

Keywords

Diamine, Diketones, Quinoxaline, Iodine Catalyst, Water, Green Method.
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  • Green Synthesis of Quinoxaline Derivatives

Abstract Views: 260  |  PDF Views: 2

Authors

Jairaj K. Dawle
Department of Chemistry, Rajshri Shahu Mahavidhyalaya, Latur, India
K. I. Momin
Department of Chemistry, K M C College, Khopoli, Dist Raigad, India
S. R. Mathapati
Department of Chemistry, S. M. P. College, Murum, Omerga, Dist: Osmanabad, India
A. S. Bondge
Department of Chemistry, Shivneri Mahavidhyalaya, Shirur, Anantpal Dist Latur, India
V. B. Suryawanshi
Department of Chemistry, K M C College, Khopoli, Dist Raigad, India

Abstract


The objective of present research work is to provide green technique for synthesis of 2,3-diphenyl quinoxaline. Quinoxaline derivatives are well known in the pharmaceutical industry. A simple, highly efficient and green procedure for the condensation of α-phenylenediamine with α-diketones in the presence of catalytic quantity of iodine. Thevery mild reaction conditions, the high yields of the products, and the use of water as solvent make this methodology an efficient and green route for synthesis of quinoxalines derivatives.

Keywords


Diamine, Diketones, Quinoxaline, Iodine Catalyst, Water, Green Method.