Biodiversity of Oxazolone Derivatives in Medicinal Chemistry:A Review

There has been keen interest in the development of novel compounds with antimicrobial, analgesic, antiinflammatory, anticancer, anti-HIV, antiangiogenic, anticonvulsant, antitumor, antagonistic and cardiotonic activity. Oxazolone, a five membered heterocyclic nucleus is a versatile lead compound for designing potent medicinally active agents. This review represents the diverse biological applications of oxazolone and their excellent performance as a substrate in the synthesis of various heterocyclic bioactive compounds, which fascinates the medicinal chemists to pursue research on this nucleus.