Synthesis, Characterization and  In-Vitro  Anti-Microbial Screening of Novel Schiff Bases of Isatin Derivatives

S. Ramachandran; Karanam Naga Kanika Raju

Vol 4, No 6 (2011)
Pages: 925-927
Published: 2011-06-01

Synthesis, Characterization and In-Vitro Anti-Microbial Screening of Novel Schiff Bases of Isatin Derivatives

S. Ramachandran ¹, Karanam Naga Kanika Raju ²

Affiliations
1 Department of Pharmaceutical Chemistry, S.B College of Pharmacy, Anaikuttam, Sivakasi, Tamilnadu, India
2 Department of Pharmaceutics, S.B College of Pharmacy, Anaikuttam, Sivakasi, Tamilnadu, India

Novel schiff bases of isatin derivatives were synthesized. The structures of these compounds were established by means of IR, ¹H-NMR analysis. All the compounds were evaluated for antimicrobial activity. Most of the compounds show significant antimicrobial activity, when compared with the standard drugs.