Microwave Assisted Synthesis and Antimicrobial Screening of Heterocyclic Compounds Comprising of Thiazolidinone Ring

In our earlier research, we have reported conventional synthesis and antioxidant activity of thiazolidinone derivatives. During various literature surveys, we found microwave technique is advantageous over conventional synthesis and various derivatives comprising of thiazolidinone group have shown good antimicrobial activity. By considering all these assumption, we have resynthesized our reported products by microwave synthesis and screened them for antimicrobial activity. The microwave assisted synthesis was found advantageous over conventional by reducing reaction time, increasing yield and lesser usage of solvent. Structures of all the synthesized compounds were confirmed by IR, ¹H NMR, and mass spectral data. The synthesized compounds were evaluated for their antimicrobial activity. Few compounds were found with potent antimicrobial activity.