Asian Journal of Research in Chemistry

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Interference Study on Artificial Sweeteners in Forensic Toxicological Screening by TLC


Affiliations
1 Central Forensic Science Laboratory, Directorate of Forensic Science, Ministry of Home Affairs, Govt. of India, Ramanthapur, Hyderabad – 500 013, India
2 Central Forensic Science Laboratory, Directorate of Forensic Science, Ministry of Home Affairs, Govt. of India, Chandigarh, India
3 Forensic science Unit, Department of Chemistry, University College of Science, Osmania University, Hyderabad – 500 007, India
     

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A study was carried out to assess the possible interference of artificial sweeteners (Saccharin, sucralose, aspartame and cyclamate) while screening for drugs and pesticides in stomach content, urine and tissues by TLC for forensic toxicological purposes. Even though these sweeteners were extractable in acidic drugs extract and pesticide extract but they did not interfere in the analysis of drugs and pesticides. Therefore the screening methods usually used in forensic toxicological analysis for drugs and pesticides can be applied as such without any modification as the artificial sweeteners were not found to interfere.


Keywords

Artificial Sweeteners, Interference, Drugs, Pesticides, Forensic Toxicological Analysis.
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  • Interference Study on Artificial Sweeteners in Forensic Toxicological Screening by TLC

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Authors

Mohd Idris
Central Forensic Science Laboratory, Directorate of Forensic Science, Ministry of Home Affairs, Govt. of India, Ramanthapur, Hyderabad – 500 013, India
S. K. Shukla
Central Forensic Science Laboratory, Directorate of Forensic Science, Ministry of Home Affairs, Govt. of India, Chandigarh, India
T. R. Baggi
Forensic science Unit, Department of Chemistry, University College of Science, Osmania University, Hyderabad – 500 007, India

Abstract


A study was carried out to assess the possible interference of artificial sweeteners (Saccharin, sucralose, aspartame and cyclamate) while screening for drugs and pesticides in stomach content, urine and tissues by TLC for forensic toxicological purposes. Even though these sweeteners were extractable in acidic drugs extract and pesticide extract but they did not interfere in the analysis of drugs and pesticides. Therefore the screening methods usually used in forensic toxicological analysis for drugs and pesticides can be applied as such without any modification as the artificial sweeteners were not found to interfere.


Keywords


Artificial Sweeteners, Interference, Drugs, Pesticides, Forensic Toxicological Analysis.