Asian Journal of Research in Chemistry

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Oxindoles and Their Pharmaceutical Significance-An Overview


Affiliations
1 Department of Pharmaceutical Sciences, School of Sciences, University of Greenwich, Chatham Maritime, Kent, ME4 4TB, United Kingdom
2 Department of Pharmaceutics, Jangaon Institute of Pharmaceutical Sciences, Kakatiya University, Yeshwanthapur, Jangaon- 506167, India
3 Sree Dattha Institute of Pharmacy, Sheriguda, Ibrahimpatnam-501510, India
4 Department of Medicinal Chemistry, Talla Padamavathi College of Pharmacy, Urus, Kareemabad-506002, India
     

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Oxindoles are credited to have a wide range of applications and are reported to exhibit an extensive range of biological effects which include the antiviral, antifungal, antibacterial, antiproliferative, anticancer, anti-inflammatory antihypertensive and the anticonvulsant activities. The chemistry of oxindoles is very interesting and the biological activity of the oxindoles and their derivatives has made them very important in synthetic organic and medicinal chemistry. This review provides insight into various applications of oxindoles and their derivatives to date.


Keywords

Oxindoles, Oxindole Derivatives, Applications, Biological Activity.
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  • Oxindoles and Their Pharmaceutical Significance-An Overview

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Authors

Shashi Ravi Suman Rudrangi
Department of Pharmaceutical Sciences, School of Sciences, University of Greenwich, Chatham Maritime, Kent, ME4 4TB, United Kingdom
Vijaya Kumar Bontha
Department of Pharmaceutics, Jangaon Institute of Pharmaceutical Sciences, Kakatiya University, Yeshwanthapur, Jangaon- 506167, India
Venkata Reddy Manda
Sree Dattha Institute of Pharmacy, Sheriguda, Ibrahimpatnam-501510, India
Srinivas Bethi
Department of Medicinal Chemistry, Talla Padamavathi College of Pharmacy, Urus, Kareemabad-506002, India

Abstract


Oxindoles are credited to have a wide range of applications and are reported to exhibit an extensive range of biological effects which include the antiviral, antifungal, antibacterial, antiproliferative, anticancer, anti-inflammatory antihypertensive and the anticonvulsant activities. The chemistry of oxindoles is very interesting and the biological activity of the oxindoles and their derivatives has made them very important in synthetic organic and medicinal chemistry. This review provides insight into various applications of oxindoles and their derivatives to date.


Keywords


Oxindoles, Oxindole Derivatives, Applications, Biological Activity.