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In Vitro Anti Oxidant Study of Ethanolic Extract of Coldenia procumbens Linn


Affiliations
1 College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences. 395, Sarojini Naidu Road, Siddhapudur, Coimbatore- 641 044, Tamil Nadu, India
2 S. B. College of Pharmacy, Sivakasi- 626130, Tamil Nadu, India
3 Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore - 641 029, Tamilnadu, India
     

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An investigation has been carried out to evaluate the in vitro antioxidant activity of ethanolic extract of Coldenia procumbens Linn by Diphenyl-1-picryl hydrazyl method (DPPH) and Nitric oxide radical scavenging inhibition activity method. Coldenia procumbens Linn has been widely used for a number of medicinal purposes especially in Siddha medicine. However, the information available on the pharmacological activity of the plant is very limited. Hence, it was proposed to carry out a preliminary in vitro analysis of the anti oxidant activity of the plant, which gave promising results. The standards used were ascorbic acid and rutin. This is the first report of the antioxidant activity of the plant.


Keywords

Coldenia Procumbens Linn, DPPH Method, Nitric Oxide Radical Scavenging Inhibition Activity Method.
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  • In Vitro Anti Oxidant Study of Ethanolic Extract of Coldenia procumbens Linn

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Authors

P. Beena
College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences. 395, Sarojini Naidu Road, Siddhapudur, Coimbatore- 641 044, Tamil Nadu, India
S. Purnima
S. B. College of Pharmacy, Sivakasi- 626130, Tamil Nadu, India
R. Kokilavani
Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore - 641 029, Tamilnadu, India

Abstract


An investigation has been carried out to evaluate the in vitro antioxidant activity of ethanolic extract of Coldenia procumbens Linn by Diphenyl-1-picryl hydrazyl method (DPPH) and Nitric oxide radical scavenging inhibition activity method. Coldenia procumbens Linn has been widely used for a number of medicinal purposes especially in Siddha medicine. However, the information available on the pharmacological activity of the plant is very limited. Hence, it was proposed to carry out a preliminary in vitro analysis of the anti oxidant activity of the plant, which gave promising results. The standards used were ascorbic acid and rutin. This is the first report of the antioxidant activity of the plant.


Keywords


Coldenia Procumbens Linn, DPPH Method, Nitric Oxide Radical Scavenging Inhibition Activity Method.