Synthesis of Biphenylamine Derivatives via Suzuki Coupling Reaction

The biphenyl amine derivatives has been prepared via suzuki coupling, oxidation of sulfide to sulfonyl and reductive amination. The palladium tetrakistriphenylphosphine was used as a catalyst in suzuki coupling. The sodium periodate and sodium triacetoxyborohydride are used as reagent in oxidation and reductive amination reactions. The intermediates are confirmed by corresponding functional peak in IR spectrum and characterization of final product were done with help of IR, ¹H NMR and mass spectral data.