Synthesis of Some New 3-(4-Phthalimidophenyl)-5-(Substituted Phenyl) 4- Isoxazoline Derivatives with Analgesic and Anti-Inflammatory Activities

The derivatives of 3-(4-phthalimidophenyl)-5-(substituted-phenyl)-4-isoxazoline were synthesized, which were screened for their analgesic and anti-inflammatory activity in test animals. The analgesic activity of all compounds were found to be higher than their anti-inflammatory activity, Compounds 3b, 3e, 3h and 3l were found to be more active among the synthesized compounds.