Asian Journal of Research in Chemistry

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Synthesis and Biological Evaluation of Some Novel Pyrimidine Derivatives


Affiliations
1 Department of Pharmaceutical Chemistry and Pharmaceutics, Dayananda Sagar College of Pharmacy, Kumaraswamy Layout, Bangalore – 560078, Karnataka State, India
     

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Pyrimidines are the class of heterocyclic compounds of pharmaceutical importance. The compounds having pyrimidine ring moiety are associated with fungicidal, anti-inflammatory, anti-HIV, antioxidant and anti-tumor activities.

In the present study, an attempt was made to synthesize and characterize substituted pyrimidine derivatives and they were screened for antimicrobial and antioxidant activities by Filter disc method and DPPH method, respectively.


Keywords

Pyrimidine, Antimicrobial Activity, Antioxidant Activity, Filter Disc Method.
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  • Synthesis and Biological Evaluation of Some Novel Pyrimidine Derivatives

Abstract Views: 264  |  PDF Views: 1

Authors

Kalpana Divekar
Department of Pharmaceutical Chemistry and Pharmaceutics, Dayananda Sagar College of Pharmacy, Kumaraswamy Layout, Bangalore – 560078, Karnataka State, India
Jani Hardik
Department of Pharmaceutical Chemistry and Pharmaceutics, Dayananda Sagar College of Pharmacy, Kumaraswamy Layout, Bangalore – 560078, Karnataka State, India
S. Brahmani Priyadarshini
Department of Pharmaceutical Chemistry and Pharmaceutics, Dayananda Sagar College of Pharmacy, Kumaraswamy Layout, Bangalore – 560078, Karnataka State, India

Abstract


Pyrimidines are the class of heterocyclic compounds of pharmaceutical importance. The compounds having pyrimidine ring moiety are associated with fungicidal, anti-inflammatory, anti-HIV, antioxidant and anti-tumor activities.

In the present study, an attempt was made to synthesize and characterize substituted pyrimidine derivatives and they were screened for antimicrobial and antioxidant activities by Filter disc method and DPPH method, respectively.


Keywords


Pyrimidine, Antimicrobial Activity, Antioxidant Activity, Filter Disc Method.