New and Efficient Route for the Synthesis of Ketone from Alkyl Halide Using 	&#945;-Chloro Nitrone as Oxidizing Reagent

Bhaskar Chakraborty; Prawin K. Sharma

Vol 4, No 1 (2011)
Pages: 95-99
Published: 2011-01-01

New and Efficient Route for the Synthesis of Ketone from Alkyl Halide Using α-Chloro Nitrone as Oxidizing Reagent

Bhaskar Chakraborty , Prawin K. Sharma

Affiliations
1 Organic Chemistry Laboratory, Sikkim Government College, Gangtok, Sikkim 737102, India

Consecutive S_N2 reaction of -chloro nitrones are studied with isopropyl halides and the nitrones are found to have remarkable oxidizing properties for the conversion of isopropyl halides to ketones with high yields. In addition, the side product obtained can serve as efficient dipolarophile in 1,3-Dipolar cycloaddition reaction to produce spiro cycloadduct in good yield.