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Synthesis and Characterization of Naphtho Fused [1,8]Naphthyridine Derivatives


Affiliations
1 Department of Chemistry (PG & Research), Kongunadu Arts and Science College, G.N. Mills (PO), Coimbatore-641 029, Tamilnadu, India
     

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2-chloro-3-formylquinoline undergo cyclo-condensation with 1-naphthylamine in presence of catalytic amount of triethylamine under reflux to afford the corresponding benzo[g]naphtho[b][1,8]naphthyrindes in excellent yields. This procedure provides a convenient method for direct synthesis of benzo and naphtho fused [1,8] naphthyrinde derivatives under thermal conditions. The structure of the synthesized compounds was confirmed by spectral and analytical data.


Keywords

Naphtho, Quinoline, Naphthyridines, Condensation.
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  • Synthesis and Characterization of Naphtho Fused [1,8]Naphthyridine Derivatives

Abstract Views: 270  |  PDF Views: 1

Authors

V. Nadaraj
Department of Chemistry (PG & Research), Kongunadu Arts and Science College, G.N. Mills (PO), Coimbatore-641 029, Tamilnadu, India
S. Thamarai Selvi
Department of Chemistry (PG & Research), Kongunadu Arts and Science College, G.N. Mills (PO), Coimbatore-641 029, Tamilnadu, India

Abstract


2-chloro-3-formylquinoline undergo cyclo-condensation with 1-naphthylamine in presence of catalytic amount of triethylamine under reflux to afford the corresponding benzo[g]naphtho[b][1,8]naphthyrindes in excellent yields. This procedure provides a convenient method for direct synthesis of benzo and naphtho fused [1,8] naphthyrinde derivatives under thermal conditions. The structure of the synthesized compounds was confirmed by spectral and analytical data.


Keywords


Naphtho, Quinoline, Naphthyridines, Condensation.