Asian Journal of Research in Chemistry

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Synthesis of 1,3,4-Oxadiazole


Affiliations
1 P.G. and Research Centre, Maulana Azad College of Arts, Science and Commerce, Aurangabad, India
     

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Synthesis of 1,3,4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1,3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized compounds were found to be 62-68%.

Keywords

Oxadiazole, Carbohydrazide, Antibacterial Activity, Antifungal Activity, Phthalyl Amino Acids.
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  • Synthesis of 1,3,4-Oxadiazole

Abstract Views: 236  |  PDF Views: 5

Authors

Maqdoom Farooqui
P.G. and Research Centre, Maulana Azad College of Arts, Science and Commerce, Aurangabad, India
Syed Nazimuddin
P.G. and Research Centre, Maulana Azad College of Arts, Science and Commerce, Aurangabad, India

Abstract


Synthesis of 1,3,4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1,3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized compounds were found to be 62-68%.

Keywords


Oxadiazole, Carbohydrazide, Antibacterial Activity, Antifungal Activity, Phthalyl Amino Acids.