Asian Journal of Research in Chemistry

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Reduction of Schiff Bases with Sodium Borohydride Possessing Antibacterial Activity


Affiliations
1 P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India
2 Department of Botany, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India
     

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A convenient synthesis of secondary amines has been prepared by the reduction of Schiff bases by using sodium borohydride as a selective reducing agent. The Schiff bases were synthesized from 2-hydroxy-3-iodo-5-phenyl benzaldehyde moiety. The structures of the compounds have been confirmed by elemental analysis and spectral data. The antibacterial activity of these compounds has also been screened.

Keywords

Schiff Bases, Secondary Amines, Sodium Borohydride, Antibacterial Activity.
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  • Reduction of Schiff Bases with Sodium Borohydride Possessing Antibacterial Activity

Abstract Views: 214  |  PDF Views: 0

Authors

S. B. Junne
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India
Archana B. Kadam
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India
Archana Y. Vibhute
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India
S. L. Shinde
Department of Botany, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India
R. B. Patil
Department of Botany, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India
Y. B. Vibhute
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-05 (M.S.), India

Abstract


A convenient synthesis of secondary amines has been prepared by the reduction of Schiff bases by using sodium borohydride as a selective reducing agent. The Schiff bases were synthesized from 2-hydroxy-3-iodo-5-phenyl benzaldehyde moiety. The structures of the compounds have been confirmed by elemental analysis and spectral data. The antibacterial activity of these compounds has also been screened.

Keywords


Schiff Bases, Secondary Amines, Sodium Borohydride, Antibacterial Activity.