Asian Journal of Research in Chemistry

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Simultaneous Spectrophotometric Estimation of Curcuminoids and Ascorbic Acid in Bulk Drug and Ayurvedic Polyherbal Tablet Dosage Form


Affiliations
1 Department of Pharmaceutical Analysis, JNTU Anantapur, OTRI Campus, Anantapur, A.P., India
2 Nalanda College of Pharmacy, Nalgonda, A.P, India
     

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In the present study, an attempt has been made to develop an analytical method for the simultaneous estimation of curcuminoids and ascorbic acid in commercially marketed ayurvedic polyherbal formulation Nisha Amalaki  vatti by spectrophotometric method. Simultaneous equations (Vierodt’s method) were performed by UV/Visible spectrophotometric. Curcuminoids has absorbance maxima at about 447 nm and Ascorbic acid maxima at about 247 nm in methanol. The linearity was obtained in the concentration range of 10-50 mcg/mL for both curcuminoids and ascorbic acid. The results were of the analysis were validated statistically and the recovery studies were carried out as per ICH guidelines.

Keywords

Curcuminoids, Ascorbic Acid, Nisha Amalaki Vatti.
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  • Simultaneous Spectrophotometric Estimation of Curcuminoids and Ascorbic Acid in Bulk Drug and Ayurvedic Polyherbal Tablet Dosage Form

Abstract Views: 194  |  PDF Views: 0

Authors

S. Rubesh Kumar
Department of Pharmaceutical Analysis, JNTU Anantapur, OTRI Campus, Anantapur, A.P., India
J. Ram Kishan
Nalanda College of Pharmacy, Nalgonda, A.P, India
K. N. Venkateshwar Rao
Nalanda College of Pharmacy, Nalgonda, A.P, India
N. Duganath
Department of Pharmaceutical Analysis, JNTU Anantapur, OTRI Campus, Anantapur, A.P., India
R. Kumanan
Department of Pharmaceutical Analysis, JNTU Anantapur, OTRI Campus, Anantapur, A.P., India

Abstract


In the present study, an attempt has been made to develop an analytical method for the simultaneous estimation of curcuminoids and ascorbic acid in commercially marketed ayurvedic polyherbal formulation Nisha Amalaki  vatti by spectrophotometric method. Simultaneous equations (Vierodt’s method) were performed by UV/Visible spectrophotometric. Curcuminoids has absorbance maxima at about 447 nm and Ascorbic acid maxima at about 247 nm in methanol. The linearity was obtained in the concentration range of 10-50 mcg/mL for both curcuminoids and ascorbic acid. The results were of the analysis were validated statistically and the recovery studies were carried out as per ICH guidelines.

Keywords


Curcuminoids, Ascorbic Acid, Nisha Amalaki Vatti.