Asian Journal of Research in Chemistry

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Reaction of Steroidal Ketones with Substituted Alkylazide


Affiliations
1 Somany Institute of Technology and Management, Rewari, India
2 Department of Chemistry, Steroidal Research Laboratory, Aligarh Muslim University, Aligarh-202002, India
     

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A series of steroidal N-2-phenylethenyl-7a-aza-B-homo-3β-acetoxycholest-5-en-7-one were prepared by the reaction of 2-hydroxy-2-phenylethylazide with steroidal α, β-unsaturated ketones in dichloromethane. Structures of all the synthesized compounds are supported by elemental analysis IR, 1HNMR and Mass Spectral studies and chemical evidences.

Keywords

Steroids, Steroidal Ketones, N-Substituted Lactams, Substituted Alkylazide.
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  • Reaction of Steroidal Ketones with Substituted Alkylazide

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Authors

Azhar U. Khan
Somany Institute of Technology and Management, Rewari, India
M. Mushfiq
Department of Chemistry, Steroidal Research Laboratory, Aligarh Muslim University, Aligarh-202002, India

Abstract


A series of steroidal N-2-phenylethenyl-7a-aza-B-homo-3β-acetoxycholest-5-en-7-one were prepared by the reaction of 2-hydroxy-2-phenylethylazide with steroidal α, β-unsaturated ketones in dichloromethane. Structures of all the synthesized compounds are supported by elemental analysis IR, 1HNMR and Mass Spectral studies and chemical evidences.

Keywords


Steroids, Steroidal Ketones, N-Substituted Lactams, Substituted Alkylazide.