UV-Spectrophotometry Estimation of Fenofibrate in Tablet Dosage Form

A new, simple, specific, sensitive, accurate, precise and economical procedure for determination of Fenofibrate in their tablet dosage form has been developed using Zero order and Second Order Derivative Method. In the proposed method, the signals of absorbance maxima were measured at 285.5 nm in methanol solvent. The method based on the native ultraviolet absorbance maxima. The drug obeyed Beer’s law in the concentration range from 03-30 μg/ml in method. The results of analysis have been validated statistically and by recovery studies. The method shows good repeatability and recovery with % RSD is less than 2. The precision and accuracy of method were confirmed by repeatability and by recovery studies.