Asian Journal of Research in Chemistry

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Synthesis and Antimicrobial Activity of 5-Substituted-2-(1-H-Benzimidazole) Sulfonamides


Affiliations
1 Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, India
     

   Subscribe/Renew Journal


Heterocyclic compounds such as 5-substituted-2-(1-H-benzimidazole) sulfonamides were synthesized by condensation of 5-substituted-2-(1-H-benzimidazole)-sulfonyl chloride and 2-aminoheterocycles with triethyl amine in dry acetone. The synthesized compounds were checked for their antimicrobial potency by screening them against two bacterial strains as well as one fungal strain. The structures of compounds have been established on the basis of their elemental analysis and spectral data.

Keywords

Sulphonamides, 2-Mercapto Benzimidazole, Antifungal, Antibacterial.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 156

PDF Views: 0




  • Synthesis and Antimicrobial Activity of 5-Substituted-2-(1-H-Benzimidazole) Sulfonamides

Abstract Views: 156  |  PDF Views: 0

Authors

Y. S. Rane
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, India
R. R. Varma
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, India
L. S. Patil
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, India
S. V. Athlekar
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, India
A. S. Chowdhary
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, India
A. S. Bobade
Department of Chemotherapy, Haffkine Institute for Training, Research and Testing, Parel, Mumbai-12, India

Abstract


Heterocyclic compounds such as 5-substituted-2-(1-H-benzimidazole) sulfonamides were synthesized by condensation of 5-substituted-2-(1-H-benzimidazole)-sulfonyl chloride and 2-aminoheterocycles with triethyl amine in dry acetone. The synthesized compounds were checked for their antimicrobial potency by screening them against two bacterial strains as well as one fungal strain. The structures of compounds have been established on the basis of their elemental analysis and spectral data.

Keywords


Sulphonamides, 2-Mercapto Benzimidazole, Antifungal, Antibacterial.