Asian Journal of Research in Chemistry

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

New Simple UV Spectrophotometric Method for Estimation of Almotriptan Malate in Bulk and Pharmaceutical Dosage Forms


Affiliations
1 Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur-522002, India
2 Department of Chemistry/Pharmacy, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur-522510, India
     

   Subscribe/Renew Journal


A new simple, sensitive, precise, accurate and economical UV spectrophotometric method of analysis for almotriptan malate both as a bulk drug and in tablet formulations was developed and validated. The method employed methanol as solvent and the drug shows maximum absorbance at 227 nm with molar absorptivity of 0.8532×105 L/mol.cm. The linear regression analysis data for the calibration plot showed good linear relationship with r2=0.9999 in the concentration range of 1-5 μg/ml. Results of analysis were validated statistically and by recovery studies.

Keywords

Almotriptan Malate, U.V Spectrophotometry, Tablets.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 231

PDF Views: 0




  • New Simple UV Spectrophotometric Method for Estimation of Almotriptan Malate in Bulk and Pharmaceutical Dosage Forms

Abstract Views: 231  |  PDF Views: 0

Authors

A. Suneetha
Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur-522002, India
B. Syama Sundar
Department of Chemistry/Pharmacy, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur-522510, India

Abstract


A new simple, sensitive, precise, accurate and economical UV spectrophotometric method of analysis for almotriptan malate both as a bulk drug and in tablet formulations was developed and validated. The method employed methanol as solvent and the drug shows maximum absorbance at 227 nm with molar absorptivity of 0.8532×105 L/mol.cm. The linear regression analysis data for the calibration plot showed good linear relationship with r2=0.9999 in the concentration range of 1-5 μg/ml. Results of analysis were validated statistically and by recovery studies.

Keywords


Almotriptan Malate, U.V Spectrophotometry, Tablets.