Asian Journal of Research in Chemistry

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Synthesis and Anti-Inflammatory Activity of Some New 2-Amino-4, 6, Diaryl Pyrimidines


Affiliations
1 Dept. of Pharma. Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India
     

   Subscribe/Renew Journal


Some new pyrimidine derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with guanidine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.

Keywords

Synthesis, Pyrimidines, Anti-Inflammatory Activity.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 148

PDF Views: 0




  • Synthesis and Anti-Inflammatory Activity of Some New 2-Amino-4, 6, Diaryl Pyrimidines

Abstract Views: 148  |  PDF Views: 0

Authors

B. Ramesh
Dept. of Pharma. Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India
R. N. Umashankar
Dept. of Pharma. Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India
S. Babitha
Dept. of Pharma. Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, India

Abstract


Some new pyrimidine derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with guanidine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.

Keywords


Synthesis, Pyrimidines, Anti-Inflammatory Activity.