Synthesis and Anti-Bacterial Study of 4-(4-Substituted Phenyl)-5,6-Disubstituted-1-(4-Substituted Phenyl Thiazol-2-Yl) Pyridin-2 (1H)-One

4-(4-Substituted Phenyl)-5,6-Disubstituted-1-(4-Substituted Phenyl Thiazol-2-yl) Pyridin-2(1H)-One have been prepared from citric acid it is treated withconc. H₂SO₄ and then with phenetole to give β-arylglutaconic acid which on fusion with 2-amino 4-substituted Phenyl thiazole results in 4-(4-substitutedphenyl)-1-(4-substitutedphenylthiazol-2-yl) pyridine-2,6 (1H,3H)-dione. Then reacted with phosphorous oxychloride, it give 5,6-dichloro-4-(4-substituted phenyl)-1-(4 substituted phenyl thiazol-2-yl) pyridin-2(1H)-one. Which on treatment with secondary amines Yields 4-(4-Substituted phenyl)-5,6-Disubstituted-1-(4-Substituted-Phenyl thiazol-2-yl)Pyridin-2(1H)-One. All the title compounds characterised on the basis of their IR, MASS, ¹H NMR spectroscopic data analysis.