Asian Journal of Research in Chemistry

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Spectrophotometric Methods for Simultaneous Estimation of Rabeprazole and Ondansetron From Combined Tablet Dosage Form


Affiliations
1 Lachoo Memorial College of Science and Technology, Pharmacy Wing, Jodhpur-342003, Rajasthan, India
2 B. R. Nahata College of Pharmacy, Mhow-Neemuch Road, Mandsaur-458001, Madhya Pradesh, India
     

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Simple, accurate, economical and reproducible spectrophotometric methods for simultaneous estimation of Rabeprazole and Ondansetron in combined tablet dosage form have been developed. The developed method employs formation and solving of simultaneous equation using two wavelengths 284.4 nm and 302.0 nm for formation of simultaneous equation. This method obeys Beer’s law in the employed concentration ranges. Results of analysis were validated statistically and by recovery studies.

Keywords

Spectrophotometric Estimation, Rabeprazole, Ondansetron.
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  • Spectrophotometric Methods for Simultaneous Estimation of Rabeprazole and Ondansetron From Combined Tablet Dosage Form

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Authors

Vankar Kaushik Kumar
Lachoo Memorial College of Science and Technology, Pharmacy Wing, Jodhpur-342003, Rajasthan, India
Nayak Diptish Kumar
Lachoo Memorial College of Science and Technology, Pharmacy Wing, Jodhpur-342003, Rajasthan, India
Shrivastava Alankar
B. R. Nahata College of Pharmacy, Mhow-Neemuch Road, Mandsaur-458001, Madhya Pradesh, India

Abstract


Simple, accurate, economical and reproducible spectrophotometric methods for simultaneous estimation of Rabeprazole and Ondansetron in combined tablet dosage form have been developed. The developed method employs formation and solving of simultaneous equation using two wavelengths 284.4 nm and 302.0 nm for formation of simultaneous equation. This method obeys Beer’s law in the employed concentration ranges. Results of analysis were validated statistically and by recovery studies.

Keywords


Spectrophotometric Estimation, Rabeprazole, Ondansetron.