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Current Advance Analytical Techniques:A Review


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1 K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai-400005, India
     

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The analytical industry today is showing a serious shift in the paradigm worldwide with advancements in technological compatibility and integration. Traditional analytical approaches including HPLC (High-Performance Liquid Chromatograph), GC (Gas Chromatograph), UV (Ultraviolet) detection, etc., have become insufficient to effectively address the growing number of challenges in analyses of species- specificity and sensitivity. This has given rise to investigate and offer highly advanced hyphenated techniques that meet the needs of high-technology oriented applications. Hyphenation-linking together of "standard" analytical techniques-generally leads to enhanced analytical performance. The biggest advantage of hyphenated speciation techniques is the ability to detect species other than the pre-conceived compounds. The advancement of analytical techniques is thus bringing a new era of development which will serve as a rapid and unambiguous tool in the drug development process.

Keywords

HTLC, OPLC, GC-MS, GC-IR, LC-MS, LC-MS/MS.
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  • Current Advance Analytical Techniques:A Review

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Authors

Mitesh D. Phale
K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai-400005, India
Dipti Korgaonkar
K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai-400005, India

Abstract


The analytical industry today is showing a serious shift in the paradigm worldwide with advancements in technological compatibility and integration. Traditional analytical approaches including HPLC (High-Performance Liquid Chromatograph), GC (Gas Chromatograph), UV (Ultraviolet) detection, etc., have become insufficient to effectively address the growing number of challenges in analyses of species- specificity and sensitivity. This has given rise to investigate and offer highly advanced hyphenated techniques that meet the needs of high-technology oriented applications. Hyphenation-linking together of "standard" analytical techniques-generally leads to enhanced analytical performance. The biggest advantage of hyphenated speciation techniques is the ability to detect species other than the pre-conceived compounds. The advancement of analytical techniques is thus bringing a new era of development which will serve as a rapid and unambiguous tool in the drug development process.

Keywords


HTLC, OPLC, GC-MS, GC-IR, LC-MS, LC-MS/MS.