Asian Journal of Research in Chemistry

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Microwave Assisted Synthesis and Antibacterial Activity of Some Bicyclic Pyrrolidines


Affiliations
1 Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530003, India
2 Enzene Biosciences Pvt. Ltd., Bangalore, India
     

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An improved method for the synthesis of bicyclic pyrrolidines utilizing microwave-assisted synthesis is described. The synthesis involves microwave irradiation of an amine, aldehyde and maleimide in one pot fashion to give the desired product. The synthesized compounds were evaluated for their antibacterial activity against ciprofloxacin.
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  • Microwave Assisted Synthesis and Antibacterial Activity of Some Bicyclic Pyrrolidines

Abstract Views: 232  |  PDF Views: 0

Authors

M. Srinivas
Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530003, India
Y. Rajendra Prasad
Department of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530003, India
S. Chandrashekaran
Enzene Biosciences Pvt. Ltd., Bangalore, India

Abstract


An improved method for the synthesis of bicyclic pyrrolidines utilizing microwave-assisted synthesis is described. The synthesis involves microwave irradiation of an amine, aldehyde and maleimide in one pot fashion to give the desired product. The synthesized compounds were evaluated for their antibacterial activity against ciprofloxacin.