Asian Journal of Research in Chemistry

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Antidiabetic Potential of Aqueous and Alcoholic Leaf Extracts of Pithecellobium dulce


Affiliations
1 Adhiparasakthi College of Pharmacy, Melmaruvathur-603319, India
2 School of Chemical and Biotechnology, SASTRA University, Thanjavur-613402, India
     

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Ethanolic and aqueous leaf extract of Pithecellobium dulce was studied for its antidiabetic activity using streptozotocin-induced diabetic model in rats. The aqueous extract showed significant activity (P<0.01) than the alcoholic extract at the tested dose level which was comparable to glibenclamide, a standard antidiabetic drug. HPTLC fingerprinting profile of the aqueous extract was also developed which would serve as reference standard for quality control of this extract.

Keywords

Alloxan, Anti-Diabetic, Leaf Extracts, Pithecellobium dulce.
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  • Antidiabetic Potential of Aqueous and Alcoholic Leaf Extracts of Pithecellobium dulce

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Authors

M. Sugumaran
Adhiparasakthi College of Pharmacy, Melmaruvathur-603319, India
T. Vetrichelvan
Adhiparasakthi College of Pharmacy, Melmaruvathur-603319, India
S. Darlin Quine
School of Chemical and Biotechnology, SASTRA University, Thanjavur-613402, India

Abstract


Ethanolic and aqueous leaf extract of Pithecellobium dulce was studied for its antidiabetic activity using streptozotocin-induced diabetic model in rats. The aqueous extract showed significant activity (P<0.01) than the alcoholic extract at the tested dose level which was comparable to glibenclamide, a standard antidiabetic drug. HPTLC fingerprinting profile of the aqueous extract was also developed which would serve as reference standard for quality control of this extract.

Keywords


Alloxan, Anti-Diabetic, Leaf Extracts, Pithecellobium dulce.