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Chemical composition and QSAR descriptor of the dichloromethane extract of Moringa olifera (L.) flowers
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The Moringa oleifera (Moringaceae) is one of these important plants, distributed in many tropical and subtropical countries, known with its medical uses of high nutritional value it is called the "tree of life". The Composition profile of the dichloromethane extract of the flowers of Moringa oleifera growing in Algerian desert was studied by capillary gas chromatography-mass spectrometry (GC-MS). thirty four Compounds were identified; Within the limits of the applied experimental conditions and by interpreting the mass spectra obtained and comparing it with the mass spectra of the reference materials, we record the possibility of the presence of the following chemical compounds: Hydrocarbons, Organic acids, Esters, Aldehydes Aromatic compounds and Nitrocyclic compounds, which major compounds are : (Z) - (9,17Octadecadienal (100%), Octadecanoic acid (60.4%), Heneicosane (10.186%), (Z)-9 Octadecenoic acid (12.711%), Heptadecanoic acid (13.742%), Hexadecane, 2,6,10,14-tetramethyl (18.988%), Heptadecane (14.866%) and Eicosane (17.535%). Analysis of QSAR descriptor from the results revealed that major constituents of the dichloromethane extract of Moringa olifera (L.) flowers
Keywords
Moringa oleifera, Dichloromethane extract, flowers, GC-MS, QSAR.
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- Aja P. M. Nwachukwu N. Ibiam U. A. Igwenyi I. O. Offor1 C. E. Orji U. O. Chemical Constituents of Moringa oleifera Leaves and Seeds from Abakaliki, Nigeria. American Journal of Phytomedicine and Clinical Therapeutics. 2014; 310-321. Available on http://www.ajpct.org/index.php/AJPCT/article/view/118/
- Jayanthi M. Satish K. Garg, Yadav P. Bhatia A. K. Goel, A. Somenewer marker phytoconstituents in methanolic extract of Moringa oleifera leaves and evaluation of its immunomodulatory and splenocytes proliferation potential in rats, Indian Journal of Pharmacology. 2015 Sep-Oct; 47(5): 518–523.doi: 10.4103/02537613.165199
- Okechukwu V. U. Eze S. O. Omokpariola D. O. and Okereke J. C. Evaluation of phytochemical constituents of Methanol extract of Moringa oleifera Lam. whole leaf by Gas Chromatography-Mass Spectrometry and Fourier transform infrared spectroscopy analysis. World News of Natural Sciences. 2021; 37: 18-30. Available on http://www.worldnewsnaturalsciences.com/wpcontent/uploads/2021/04/ WNOFNS -37-2021-18-30.pdf
- Al-Owaisi M. Al-Hadiwi N. Alam Khan S. GC-MS analysis determination of total phenolics, flavonoid content and free radical scavenging activities of various crude extracts of Moringa peregrina (Forssk.) Fiori leaves. Asian Pacific Journal of Tropical Biomedicine. 2014; 4(12): 964-970. https://doi.org/10.12980/APJTB.4.201414B295
- Khan W. Parveen R. Chester K. Parveen S. Sayeed A., Hypoglycemic Potential of Aqueous Extract of Moringa oleifera Leaf and In Vivo GC-MS Metabolomics, Frontiers in Pharmacology. 2017; 8:1-16.
- https://doi.org/10.3389/fphar.2017.00577
- Enas J. Kadhim, Duha A. AL-Shammaa, Phytochemical Characterization using GC-MS Analysis of Methanolic Extract of Moringa oleifera (Family Moringaceae) Plant Cultivated in Iraq, 2014, Chemistry and Materials Research, 6(5), pp9-26. Available onhttps://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.839. 4353&rep=rep1&type=pdf
- Karthika S. Ravishankar M. Mariajancyrani J. Chandramohan G. Study on phytoconstituents from Moringa oleifera leaves, Asian Journal of Plant Science and Research. 2013; 3(4):63-69.
- Zongo U. Zoungrana S. L. Savadogo A. Alfred S. Traoré Nutritional and Clinical Rehabilitation of Severely Malnourished Children with Moringa oleifera Lam. Leaf Powder in Ouagadougou (Burkina Faso). Food and Nutrition Sciences. 2013; 4: 991-997. doi:10.4236/fns.2013.49128
- Shih M.C. Chang C.M. Kang S.M. Tsai M.L. Effect of Different Parts (Leaf, Stem and Stalk) and Seasons (Summer and Winter) on the Chemical Compositions and Antioxidant Activity of Moringa oleifera. International Journal of Molecular Sciences 2011;12: 6077–6088. doi:10.3390/ijms12096077
- Iqbal S. Bhanger M.I. Effect of season and production location on antioxidant activity of Moringa oleifera leaves grown in Pakistan. Journal Food Composition and Analysis 2006; 19: 544–551. https://doi.org/10.1016/j.jfca.2005.05.001
- Falowo A. B. Muchenje V. Hugo A. Aiyegoro O. A. Fayemi P. O. Antioxidant activities of Moringa oleifera L. and Bidens pilosa L. leaf extracts and their effects on oxidative stability of ground raw beef during refrigeration storage. cyta – journal of food. 2017; 15(2): 249–256. http://dx.doi.org/10.1080/19476337.2016.1243587
- Benarima A. Laouini S. E. Raache M. N. Kouadri M. R. Influence of Extraction temperature on the Phenolic compounds and Antioxidant Capacity from Moringa oleifera Leaves. Asian Journal of Research Chemistry. 2021; 14(2):120-124. doi: 10.5958/09744150.2021.00022.5
- P, A., K, S., and C, S. GC-MS Profiling and Antioxidant Activities of Ethanol Extract of Fresh Seeds of Miracle Tree-Moringa Oleifera lam. Asian Journal of Pharmaceutical Research and Development. 2020; 8(4): 58-66. https://doi.org/https://doi.org/10.22270/ajprd.v8i4.783
- Arumugam P. Saraswathi K. Sivaraj C. GC-MS Profiling and Antioxidant Activities of Ethanol Extract of Fresh Seeds of Miracle Tree-Moringa Oleifera lam., Asian Journal of Pharmaceutical Research and Development. 2020; 8(4):58-66. http://www.ajprd.com/index.php/journal/article/download/783/646
- Mahdi H.J. Khan N.A.K. Asmawi M.Z.B. Mahmud R. Murugauyah V.A. In vivo, anti-arthritic and anti-noceciptive effects of ethanol extract of Moringa oleifera, leaves on complete Freund’s adjuvant (CFA)-induced arthritis in rats. Integrative Medicine Research. 2018; 7: 85–94. DOI: 10.1016/j.imr.2017.11.002
- Cheenpracha S. Park E.J. Yoshida W.Y. Barit C. Wall M. Pezzuto J.M. Chang L.C. Potential anti-inflammatory phenolic glycosides from the medicinal plant Moringa oleifera fruits. Bioorganic and medicinal chemistry. 2010; 18: 6598–6602. DOI: 10.1016/j.bmc.2010.03.057
- Sreelatha S. Jeyachitra A. Padma P.R. Antiproliferation and induction of apoptosis by Moringa oleifera leaf extract on human cancer cells. Food and Chemical Toxicology. June 2011 ; 49(6): 1270–1275. https://doi.org/10.1016/j.fct.2011.03.006
- Tragulpakseerojn J. Yamaguchi N. Pamonsinlapatham P. Wetwitayaklung P. Yoneyama T. Ishikawa N. Ishibashi M. Apirakaramwong A. Anti-proliferative effect of Moringa oleifera Lam (Moringaceae) leaf extract on human colon cancer HCT116 cell line. Tropical Journal of Pharmaceutical Research. February 2017; 16: 371–378. http://dx.doi.org/10.4314/tjpr.v16i2.16
- Kajihara R. Nakatsu S. Shiono T. Ishihara M. Sakamoto K. Muto N. Antihypertensive Effect of Water Extracts from Leaves of Moringa oleifera Lam. on Spontaneously Hypertensive Rats. Nippon Shokuhin Kagaku Kogaku Kaishi. 2008; 55: 183–185. DOI: https://doi.org/10.3136/nskkk.55.183
- Helmy S.A. Nfs M. Elaby S.M. Ghally M.A.A. Hypolipidemic Effect of Moringa oleifera Lam Leaf Powder and its Extract in Diet-Induced Hypercholesterolemic Rats. Journal of Medicinal Food. 2017; 20:755–762. DOI: 10.1089/jmf.2016.0155
- Dharmendra S. Vrat A.P. Prakash A.V. Radhey S.G. Evaluation of Antioxidant and Hepatoprotective Activities of Moringa oleifera Lam. Leaves in Carbon Tetrachloride-Intoxicated Rats. Antioxidants. 2014; 3:569–591. DOI: 10.3390/antiox3030569
- Villarruel-López A. Mora L.L. Vázquez-Paulino O.D. PueblaMora A.G. Torres-Vitela, M.R. Guerrero-Quiroz L.A. Nuño K. Effect of Moringa oleifera consumption on diabetic rats. BMC Complementary and Alternative Medicine. 2018; 18:127,1-10. DOI: 10.1186/s12906-018-2180-2
- Singh R.S.G. Negi P.S. Radha C. Phenolic composition antioxidant and antimicrobial activities of free and bound phenolic extracts of Moringa oleifera seed flour. Journal of Functional Foods. 2013; 5:1883–1891. https://doi.org/10.1016/j.jff.2013.09.009
- Pal S.K. Mukherjee P.K. Saha K. Pal M. Saha B.P. Antimicrobial action of the leaf extract of Moringa oleifera lam., Ancient Science of Life. 1995;14(3):197–199. Available on https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331240/pdf/ASL -14-197.pdf
- Omokpariola D. O. Precious-Egere S. C. Omokpariola P. L. Okechukwu V.U. Phytochemical and Anti-Microbial Analysis of Metabolites in seeds of Moringa oleifera grown in Nigeria, Progress in Chemical and Biochemical Research 2021; 4(3):268277. Available on http://www.pcbiochemres.com/article_131612_2923e3ddd99a3f60 934a364fd4d5f403.pdf
- Selvakumar D. Natarajan P. Hepato-Protective activity of Moringa oleifera Lam Leaves in Carbon tetrachloride induced HepatoToxicity in Albino Rats. Pharmacognosy Magazine. 2008; 4(13):97–98.
- Siddiqui S. Upadhyay S. Rumana A. Barkat Md. A. Azfar J. Alothaim A. S. Mohd. Zaheen H. Rahman M.A. Md Arshad Tanveer A. Khan M. F. Hari S. Sarjeel Kaleem M. A. Jalal A. Interaction of Bioactive Compounds of Moringa oleifera Leaves with SARS CoV 2 Proteins to Combat COVID 19 Pathogenesis: a Phytochemical and In Silico Analysis. Applied Biochemistry and Biotechnology, https://doi.org/10.1007/s12010-022-04040-1
- Shunmugapriya K. Vennila P. Kanchana S. Vellaikumar S. Identification of Volatile Flavour Compounds in Moringa Oleifera Powder and Soup Mixes, Chemical Science Review and Letters. 2020; 9 (33):162-170. DOI:10.37273/chesci.CS20510110
- Aduseia S. Azupiob S. Tei-Mensahc E. MacCarthyd C. Akomeng N. Phytochemistry nutritional composition and pharmacological potential of Moringa oleifera: A comprehensive review, International journal of plant based pharmaceuticals.2022;2(2):228-238. https://doi.org/10.29228/ijpbp.5.
- Chandrawati Jee N. Kumar R. Gas Chromatography Study of Methanolic Leave Extract of Moringa oleifera Lam. International Journal of Current Microbiology and Applied Sciences. 2020; 9(2): 2590-2595. https://doi.org/10.20546/ijcmas.2020.902.295
- Amaechi NC. Evaluation of Bioactive Compounds in Moringa oleifera Flower Using Gas Chromatography Mass Spectrometry/Fourier Transform Infrared Spectroscopy: The Need for Good Postharvest Handling. Acta Scientific Nutritional Health, 2021; 5(12): 112-122. DOI: 10.31080/ASNH.2020.05.0967
- Hasriana H., et al. GC-MS Analysis and In Vitro Antioxidant Activity of Crude Extracts and Different Fractions of Moringa Oleifera Pods. Materials Science Forum. vol. 1025. Trans Tech Publications Ltd. Mach 2021; 247–251. doi:10.4028/www.scientific.net/msf.1025.247.
- Hongqiang L. Hailin Z. Jing T. Wang H. Wang Z. Li P., Chunfang Z. Jinping L. Comparative Analysis of Chemical Constituents of Moringa oleifera Leaves from China and India by UltraPerformance Liquid Chromatography Coupled with QuadrupoleTime-Of-Flight Mass Spectrometry, Molecules, 2019; 942:1-25.
- doi:10.3390/molecules24050942
- Shunmugapriya K, Vennila P, Thirukkumar S and Ilamaran M, Identification of bioactive components in Moringa oleifera fruit by GC-MS, Journal of Pharmacognosy and Phytochemistry 2017; 6(3): 748-751. Available on https://www.phytojournal.com/archives/2017/vol6issue3/PartL/6- 3-104-681.pdf
- Ahmadu T. Ahmad K. Ismail S. I. Rashed O. N. Asib Omar D. Antifungal efficacy of Moringa oleifera leaf and seed extracts against Botrytis cinerea causing gray mold disease of tomato (Solanum lycopersicum L.). Brazilian Journal of Biology. 2021; 81(4) :1007-1022. DOI: 10.1590/1519-6984.233173
- Aldakheel R. K., Rehman S., Almessiere M. A., Khan F. A. Gondal M. A., Mostafa A. Baykal A. Bactericidal and In Vitro Cytotoxicity of Moringa oleifera Seed Extract and Its Elemental Analysis Using Laser-Induced Breakdown Spectroscopy Pharmaceuticals. 2020;13, 193:1-18. DOI: 10.3390/ph13080193
- Mathivanan D. Suseem S. R. Identified bioactive constituents on leaf of Andrographis echiodies grown on Vellore District, Tamil Nadu, Der Pharmacia Lettre. 2015; 7(12): 138-147. Available on
- https://www.scholarsresearchlibrary.com/articles/identifiedbioactive-constituents-on-leaf-of-andrographis-echiodies-grownon-vellore-district-tamil-nadu.pdf
- Abubakar M. N. Runner R. T. Majinda. GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia (Schumach) and Pterocarpus angolensis (DC). Medicines. 2016; 28:3(1):3, 1-9. doi: 10.3390/medicines3010003.
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