Asian Journal of Research in Chemistry

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A Review on 1,3,4-Thiadiazoles


Affiliations
1 Dept. Of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet, Kadapa, 516150
     

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Heterocyclic compounds occupy a central position among those molecule that makes life possible. The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4-thiadiazole constitutes constituents an important class of compounds for new drug development. The synthesis of novel thiadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. During the recent years there has been intense investigation of different classes of thiadiazole compounds, many of which possess extensive pharmacological activities. Among of these compounds having1,3,4,- thiadiazole nucleus are known to exhibit unique Antioxidant/radio protective activity, In vitro inhibition of cyclo oxygenase and 5-lipoxygenase activities, Molluscicidal activity, Carbonic anahydrase inhibitors, Anti-cancer activity, Anti convulsant activity ,Antifungal activity, Anti bacterial activity, Anti cholinergic activity, Anti histaminic activity, Anti-depressant activity, Anti-tuberculosis activity The present review highlights the recently synthesized thiadiazole possessing important biological activities

Keywords

1,3,4-thiadiazoles, Anti Fungal Activity, Molluscicidal Activity, Carbonic Anahydrase Inhibitors, Anticancer Activity, Anti Convulsant Activity
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  • A Review on 1,3,4-Thiadiazoles

Abstract Views: 397  |  PDF Views: 2

Authors

Y. Pradeep Kumar
Dept. Of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet, Kadapa, 516150
Dr. M. Sreenivasulu
Dept. Of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet, Kadapa, 516150
R. Yasmeen
Dept. Of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet, Kadapa, 516150
V. Ramya Smruthiraj
Dept. Of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet, Kadapa, 516150
V. Swathi
Dept. Of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet, Kadapa, 516150

Abstract


Heterocyclic compounds occupy a central position among those molecule that makes life possible. The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4-thiadiazole constitutes constituents an important class of compounds for new drug development. The synthesis of novel thiadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. During the recent years there has been intense investigation of different classes of thiadiazole compounds, many of which possess extensive pharmacological activities. Among of these compounds having1,3,4,- thiadiazole nucleus are known to exhibit unique Antioxidant/radio protective activity, In vitro inhibition of cyclo oxygenase and 5-lipoxygenase activities, Molluscicidal activity, Carbonic anahydrase inhibitors, Anti-cancer activity, Anti convulsant activity ,Antifungal activity, Anti bacterial activity, Anti cholinergic activity, Anti histaminic activity, Anti-depressant activity, Anti-tuberculosis activity The present review highlights the recently synthesized thiadiazole possessing important biological activities

Keywords


1,3,4-thiadiazoles, Anti Fungal Activity, Molluscicidal Activity, Carbonic Anahydrase Inhibitors, Anticancer Activity, Anti Convulsant Activity

References