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Novel Heterocyclic Compounds: Synthesis, Characterization and Biological Evaluation
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A series of chalcones were prepared by using o- hydroxyl acetophenone. The physical characterization of synthesized compounds was carried out by their Melting point and TLC. The synthesized compounds were characterized by means of their IR, <SUP>1</SUP>H-NMR spectral data. All the compounds were tested for their antibacterial and antifungal activities by the cup plate method.
Keywords
Hetrocyclic, Chalcone, Synthesis, Antibacterial Activity, Antifungal Activity, IR, NMR
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- Goodman, MS.; Rose, SD. Molecular recognition of a pyrimidine dimer and photosensitized dimer splitting by a macrocyclic bis(diaminopyridine)J. Am. Chem. Soc. 1991, 113, 9380-9382.
- Hung, C.; Hopfner, T.; Thummel, RP. Molecular recognition: consideration of individual hydrogen-bonding interactions J. Am. Chem. Soc. 1993, 115, 12601-12602.
- Schmidtchen, FP.; Gleich, A.; Schummer, Selective molecular hosts for anions A. Pure Appl. Chem. 1989, 61, 1535-1547.
- Y. Rajendra prasad, A. Lakshmana Rao and R.Rambabu, Synthesis and Antimicrobial Activity ofSome Chalcone Derivatives, E.J. Chem., 2008 ,5 (3),461-466.
- Silvia N. López, María V. Castelli, Susana A. Zacchino, José N. Domínguez, Gricela Lobo, JaimeCharris-Charris, Juan CG. Cortés, Juan C. Ribas, Cristina Devia, Ana M. Rodríguez, Ricardo D. Enriz, In vitro antifungal evaluation and structureactivity relationships of a new series of chalcone derivatives and synthetic analogues, with inhibitory properties against polymers of the fungal cell wall, Bioorg. Med. Chem. 2001,9,1999-2013.
- Bhagyesh Baviskar, Sureshbhi Patel, Bhushan Baviskar, S.S. Khadabadi, Mahendra Shiradkar, Design and Synthesis of Some Novel Chalcones as Potent Antimicrobial Agent, Asian J. Res. Chem., 2008,1(2),67-69.
- Felipe Herencia, M. Luisa Ferrandiz, Amalia Ubeda, Jose N. Domínguez, Jaime E. Charris, Gricela M. Lobo, M. Jose Alcaraz, Synthesis and anti- inflammatory activity of chalcone derivatives, Bioorg. Med. Chem. Lett., 1998,8,1169-1174.
- Xiang Wu, Prapon Wilairat, Mei-Lin Go, Anti malarial Activity Of Ferrocenyl Chalcones, Bioorg. Med. Chem. Lett. 2002,12(17),2299-2302.
- Anu Agarwal, Kumkum Srivastava, S.K. Puri, Prem M.S. Chauhan,Synthesis of 4-pyrido-6-aryl-2- substituted amino pyrimidines as a new class of antimalarial agents, Bioorg. Med. Chem., 2005 ,13, 6226-6232.
- Todigoppula Narender, Tanvir Khaliq, Shweta, Nishi, Neena Goyal, Suman Gupta. Synthesis of chrominochalcone and evaluation of their in vitro antileishmanial activity, Bioorg. Med. Chem., 2005,13,6543-6550.
- Jen-Hao Cheng, Chi-Feng Hung, Shyh-Chyun Yang, Jih-Pyang Wang, Shen-Jeu Won, Chun-Nan Lin, Synthesis And Cytotoxic, Anti-Inflammatory, And Anti-Oxidant Activities Of 2,5- Dialkoxyl chalcones As Cancer Chemopreventive Agents, Bioorg. Med. Chem., 2008,16(15),7270-7276.
- Yuh-Meei Lin, Yasheen Zhou, Michael T. Flavin, Li-Ming Zhou, Weiguo Nie, Fa-Ching Chen, Chalcones and flavonoids as anti- Tuberculosis agents, Bioorg. Med. Chem., 2002,10,2795-2802.
- Sivakumar PM, Prabu Seenivasan V, Vanaja Kumar, Mukesh Doble, Synthesis, antimycobacterial activity evaluation, and QSAR studies of chalcones derivatives Bioorg. Med. Chem. Lett., 2007,17,1695-1700.
- Saisivam S, and Kishan VB, Standard method of antifungal activity, Ind J.Microbio., 2006, 46(2),P.13-19.
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