Asian Journal of Research in Chemistry

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Synthesis and Characterization of Novel Bio-Elastomers for Tissue Engineering


Affiliations
1 PG and Research Department of Chemistry, Presidency College, Chennai – 600 005
     

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Biodegradable elastomers have recently found widespread application in many areas of biomedical engineering such as tissue engineering, therapeutic delivery and bioimaging. Recent developments led to development of elastomers involving citric acid based polyesters are being explored that are endogenous to the human metabolism. In terms of mechanical stability, crystallinity, hydrophobicity and biocompatibility, polyesters synthesised from these monomers can display a wide range of applications. In this investigation, a series of novel bio-elastomers based on citric acid were synthesised by catalyst free polycondensation reaction. These polymers were characterised by solubility, IR, 1H NMR spectral analysis, thermal and mechanical studies. The physicochemical properties of the synthesised polymers are controlled by the variation of monomers in polycondensation reaction forms a pivotal role in the synthesis.

Keywords

Biodegradable Elastomers, Biocompatibility, Polycondensation, Spectral Analysis
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  • Synthesis and Characterization of Novel Bio-Elastomers for Tissue Engineering

Abstract Views: 303  |  PDF Views: 2

Authors

R Indira
PG and Research Department of Chemistry, Presidency College, Chennai – 600 005
G Harihara Priya
PG and Research Department of Chemistry, Presidency College, Chennai – 600 005
T Tamizharuvi
PG and Research Department of Chemistry, Presidency College, Chennai – 600 005
V Jaisankar
PG and Research Department of Chemistry, Presidency College, Chennai – 600 005

Abstract


Biodegradable elastomers have recently found widespread application in many areas of biomedical engineering such as tissue engineering, therapeutic delivery and bioimaging. Recent developments led to development of elastomers involving citric acid based polyesters are being explored that are endogenous to the human metabolism. In terms of mechanical stability, crystallinity, hydrophobicity and biocompatibility, polyesters synthesised from these monomers can display a wide range of applications. In this investigation, a series of novel bio-elastomers based on citric acid were synthesised by catalyst free polycondensation reaction. These polymers were characterised by solubility, IR, 1H NMR spectral analysis, thermal and mechanical studies. The physicochemical properties of the synthesised polymers are controlled by the variation of monomers in polycondensation reaction forms a pivotal role in the synthesis.

Keywords


Biodegradable Elastomers, Biocompatibility, Polycondensation, Spectral Analysis

References