Synthesis and Evaluating Anti-Inflammatory, Antibacterial Activity of Substituted Benzylidene Thiazolidinediones

This compound we synthesize by a Knoevenagel condensation of 4-aminobenzaldehyde with compound (I) in presence of sodium acetate, but this compound do not comply with the primary aromatic amine test like nitrous acid test and carbylamine test as well as H¹ NMR spectra, in this reaction the amine group of benzaldehyde was further reacted another molecules of aldehydes. We modified the process and synthesized compound (Ia), the nitro group of compound Ia was converted in amino group by reduction.