Asian Journal of Research in Pharmaceutical Sciences

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Antihepatotoxicity of Hygrophila auriculata on CCl4 Induced Hepatotoxicity in Rats


Affiliations
1 PG & Research Department of Biochemistry, Enathi Rajappaa College, Enathi, Pattukkottai, Thanjavur Dt., Tamil Nadu, 614 615, India
     

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The objective of this study was to investigate the hepatoprotective activity of crude aqueous extract of leaves of Hygrophila auriculata against CCl4 induced hepatotoxicity. The leaves was dried in shade, they were powdered and Extracted with aqueous. The biochemical markers of hepatic damage like tested as MDA, GSH, Protein, Bilirubin, SGOT, ALP and SGPT recorded a significant alteration in CCl4 treated rats. However treatment with Hygrophila auriculata restored the level to near normal was observed. The potential hepatoprotective activity of Hygrophila auriculata is due to the presence of phytochemical constitution such as flavonoids and polyphenolic compounds present in plant.

Keywords

Hepatoprotective, CCl4-Induced, Hygrophila auriculata.
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  • Antihepatotoxicity of Hygrophila auriculata on CCl4 Induced Hepatotoxicity in Rats

Abstract Views: 236  |  PDF Views: 1

Authors

T. S. Dhanaraj
PG & Research Department of Biochemistry, Enathi Rajappaa College, Enathi, Pattukkottai, Thanjavur Dt., Tamil Nadu, 614 615, India
R. Gowthami
PG & Research Department of Biochemistry, Enathi Rajappaa College, Enathi, Pattukkottai, Thanjavur Dt., Tamil Nadu, 614 615, India
S. Rajlakshmi
PG & Research Department of Biochemistry, Enathi Rajappaa College, Enathi, Pattukkottai, Thanjavur Dt., Tamil Nadu, 614 615, India
K. Murugaiah
PG & Research Department of Biochemistry, Enathi Rajappaa College, Enathi, Pattukkottai, Thanjavur Dt., Tamil Nadu, 614 615, India

Abstract


The objective of this study was to investigate the hepatoprotective activity of crude aqueous extract of leaves of Hygrophila auriculata against CCl4 induced hepatotoxicity. The leaves was dried in shade, they were powdered and Extracted with aqueous. The biochemical markers of hepatic damage like tested as MDA, GSH, Protein, Bilirubin, SGOT, ALP and SGPT recorded a significant alteration in CCl4 treated rats. However treatment with Hygrophila auriculata restored the level to near normal was observed. The potential hepatoprotective activity of Hygrophila auriculata is due to the presence of phytochemical constitution such as flavonoids and polyphenolic compounds present in plant.

Keywords


Hepatoprotective, CCl4-Induced, Hygrophila auriculata.