Asian Journal of Research in Pharmaceutical Sciences

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Nanoparticle- A Review


Affiliations
1 Department of Quality Assurance Technique, R. G. Sapkal college of Pharmacy, Anjaneri Nashik, India
2 Depatment of Pharmaceutical chemistry, R.G. Sapkal college of Pharmacy Anjaneri, Nashik, India
     

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Nanotechnology refers to the creation and utilization of materials whose constituents exist at the nanoscale; and, by convention, be up to 100 nm in size. Nanotechnology explores electrical, optical, and magnetic activity as well as structural behaviour at the molecular and submolecular level. It has the potential to revolutionize a series of medical and biotechnology tools and procedures so that they are portable, cheaper, safer, and easier to administer. Nanoparticles are being used for diverse purposes, from medical treatments, using in various branches of industry production such as solar and oxide fuel batteries for energy storage, to wide incorporation into diverse materials of everyday use such as cosmetics or clothes, optical devices, catalytic, bactericidal, electronic, sensor technology, biological labelling and treatment of some cancers. Due to their exceptional properties including antibacterial activity, high resistance to oxidation and high thermal conductivity, nanoparticles have attracted considerable attention in recent years. Nanoparticles can be synthesized chemically or biologically. Metallic nanoparticles that have immense applications in industries are of different types, namely, Gold, Silver, Alloy, magnetic etc. This study aims to present an overview of nanoparticles, with special reference to their mechanism of biosynthesis and types.

Keywords

Nanoparticles, Silver, Bactericidal, Thermal Conductivity, Optical Devices.
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  • http://www.cientifica.com/archives/000081.html

  • Melgardt M de Villiers. Pharm Tech 2008; 98

  • Birrenbach G and Speicer R. J Pharm Sci 1976; 65: 1763.

  • Kreuter J. Nanoparticles. In Colloidal drug delivery systems, J, K., Ed. Marcel Dekker: New York, 1994; pp 219-342.

  • Kompella UB, Bandi N, Ayalasomayajula SP. Poly (lactic acid) nanoparticles for sustained release of budesonide. Drug Delivery Technol. 2001; 1: 1-7.

  • Ravi MN, Bakowsky U, Lehr CM. Preparation and characterization of cationic PLGA nanospheres as DNA carriers. Biomaterials 2004; 25: 1771-1777.

  • Li YP, Pei YY, Zhou ZH, Zhang XY, Gu ZH, Ding J, Zhou JJ, Gao, XJ, PEGylated polycyanoacrylate nanoparticles as tumour necrosis factor-[alpha] carriers. J Control Release 2001; 71: 287-296.

  • Kwon, HY, Lee JY, Choi SW, Jang Y, Kim JH. Preparation of PLGA nanoparticles containing oestrogen by emulsification-diffusion method. Colloids Surf. A: Physicochem. Eng. Aspects 2001; 182: 123-130.

  • Zambaux M, Bonneaux F, Gref R, Maincent P, Dellacherie E, Alonso M, Labrude P, Vigneron C. Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by double emulsion method. J. Control. Release 1998; 50: 31-40.

  • Zhang Q, Shen Z, Nagai T. Prolonged hypoglycaemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats. Int. J. Pharm. 2001; 218: 75-80.

  • Boudad H, Legrand P, Lebas G, Cheron M, Duchene D, Ponchel G. Combined hydroxypropyl-[beta]- cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir. Int J. Pharm. 2001; 218: 113-124.

  • Puglisi G, Fresta M, Giammona G, Ventura CA. Influence of the preparation conditions on poly(ethylcyanoacrylate) nanocapsule formation. Int. J. Pharm. 1995; 125: 283-287.

  • Calvo P, Remunan-Lopez C, Vila-Jato JL, Alonso MJ. Novel hydrophilic chitosan-polyethylene oxide nanoprticles as protein carriers. J. Appl. Polymer Sci. 1997; 63: 125-132.

  • Calvo P, Remunan-Lopez C, Vila-Jato JL, Alonso MJ. Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines. Pharm Res. 1997; 14: 1431-1436.

  • Torche A-M, Ex vivo and in situ PLGA microspheres uptake by pig ileal Peyer’s patch segment., Int J Pharm 2000, 201, 15–27.

  • Majeti N.V., Kumar Ravi, Kumar Neeraj, Domb. A.J., Arora Meenakshi, Pharmaceutical polymeric controlled drug delivery systems, Adv.in polymer Sci., 2012, 160, 47-108.

  • Kwon H-Y., Preparation of PLGA nanoparticles containing estrogen by emulsification–diffusion method, Colloids Surf. Release, 2001, 182, 123–30.

  • York A.W.,.KirklandS.E., McCormick C.L., Adv, Drug. Delivery, 2008, 60, 1018-1036 1036.

  • Muller RH, Bohm B etal. Nanosuspensions :A formulations approach for poorly soluble and poorly bioavailable drugs. In: DL Wise, Editor, Handbook of pharmaceutical released technology I stEdn, Marcel Dekker, New York, 2002: 345-357.

  • Duchene D, Ponchel G. Eur J Pharma Biopharma 1997; 44: 1523.

  • Liversidge GC. Drug Nanocrystals for Improved Drug Delivery, In: IntSymp Control Release Bioact Matter, Workshop on particulate drug delivery system 1996, pp.23.

  • Hameed Hyder MA. Nanotechnology and Environment: Potential applications and environmental implications of nanotechnology.www.nanoforum.de/datenien, 2003

  • Calvo P, Remunan-Lopez C, Vila-Jato JL, Alonso MJ. Novel hydrophilic chitosan-polyethylene oxide nanoprticles as protein carriers. J. Appl. Polymer Sci. 1997; 63: 125-132.

  • Thote AJ, Gupta RB. Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release. Nanomedicine: Nanotech. Biology Medicine 2005; 1: 85-90.

  • Desai MP, Labhasetwar V, Walter E, Levy RJ, Amidon G L, The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharm Res 1997; 14: 1568-73

  • Shiv Shankara S., Akhilesh Rai, Absar Ahmad, MuraliSastrya, J. of Colloid and Interface Science, 275(2), (2004)

  • Sastry M., Ahmad A., Khan I. and Kumar R., Biosynthesis of metal nanoparticles using fungi and actinomycete, CurrSci, 85(2), 162-70, (2003)

  • Abhilash M. Potential applications of Nanoparticles. Int J Pharm Bio Sci 1(1)2010.

  • Kayser.O, A. Lemke and N. Hernández-Trejo. (2005) The Impact of nanobiotechnology on the development of new drug delivery systems. Current Pharmaceutical Biotechnology 6(1), 35.

  • Ghosh. PK Hydrophilic polymeric nanoparticles as drug carriers. Indian J BiochemBiophys 2000 (37), 273-282.

  • Haltner E., EassonJ., LehrC., Lectins and bacterial invasion factors for controlling endo- and transcytosis of bioadhesive drug carrier systems. Eur. J. Pharm. Biopharm, 44, 1997, 3-13.

  • Hedley M., CurleyJ., UrbanR., Microspheres containing plasmidencoded antigens elicit cytotoxic T-cell responses. Nat Med, 4, 1998, 365-368.


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  • Nanoparticle- A Review

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Authors

Sarika V. Khandbahale
Department of Quality Assurance Technique, R. G. Sapkal college of Pharmacy, Anjaneri Nashik, India
R. B. Saudagar
Depatment of Pharmaceutical chemistry, R.G. Sapkal college of Pharmacy Anjaneri, Nashik, India

Abstract


Nanotechnology refers to the creation and utilization of materials whose constituents exist at the nanoscale; and, by convention, be up to 100 nm in size. Nanotechnology explores electrical, optical, and magnetic activity as well as structural behaviour at the molecular and submolecular level. It has the potential to revolutionize a series of medical and biotechnology tools and procedures so that they are portable, cheaper, safer, and easier to administer. Nanoparticles are being used for diverse purposes, from medical treatments, using in various branches of industry production such as solar and oxide fuel batteries for energy storage, to wide incorporation into diverse materials of everyday use such as cosmetics or clothes, optical devices, catalytic, bactericidal, electronic, sensor technology, biological labelling and treatment of some cancers. Due to their exceptional properties including antibacterial activity, high resistance to oxidation and high thermal conductivity, nanoparticles have attracted considerable attention in recent years. Nanoparticles can be synthesized chemically or biologically. Metallic nanoparticles that have immense applications in industries are of different types, namely, Gold, Silver, Alloy, magnetic etc. This study aims to present an overview of nanoparticles, with special reference to their mechanism of biosynthesis and types.

Keywords


Nanoparticles, Silver, Bactericidal, Thermal Conductivity, Optical Devices.

References